minispec

Quality Control

The minispec is useful for QA/QC in production of a variety of products, such as fats, seeds, manufactured fibers, polymers, and many more.

Non-Destructive

TD-NMR is a fast measurement technique which doesn’t cause any damage the to sample.

Research

Relaxometry is a reliable technique for for differentiation, characterization and quantification of molecular components.

Quantitative

The minispec can provide quantitative information at a high degree of accuracy.

TD NMR, or Time-Domain Nuclear Magnetic Resonance, is a powerful analytical technique used in chemistry and materials science. By subjecting samples to strong magnetic fields and radiofrequency pulses, TD NMR provides insights into molecular structure, dynamics, and interactions. It's widely applied in fields like pharmaceuticals, polymers, food industry and environmental science for tasks ranging from quality control to structural analysis.

minispec Portfolio

Applications

Determining different drug component ratios

Easy-to-use benchtop NMR system to determine the ratio of either different drug components or various solid forms in a substance.

Contactless Check Weighing

Bench-top, at-line minispec TD-NMR instrument for a fast quantitative analysis of in-package products across various application fields.

Solid Fat Content (TD-NMR)

QC applications such as the total fat determination as well as the droplet-size determination of dairy products like mayonnaise and margarine.

Total Fat and Moisture (TD-NMR)

Total Fat and Moisture by TD-NMR measured in a few seconds with minimum calibration efforts

Dynamic Fat Crystallization (TD-NMR)

For manufacturers who need to make timely decisions on the quality of fat ingredients used in their products, Bruker now offers a new method for the characterization of crystallization in less than two hours.

Seeds Analyzer (TD-NMR)

The Analyzer for your Oil and Moisture Analysis in Seeds and Nuts

Droplet Size in Emulsions (TD-NMR)

New TD-NMR solution for Droplet Size Analysis - Introducing GoScan for minispec and improved data analysis

Application Notes

TD-NMR TO QUANTIFY COMPONENTS IN SOLID MIXTURES

Characterizing the polymorphic forms of candidate pharmaceuticals is critical for success early in the drug development process. Newly proposed strategies using time-domain nuclear magnetic resonance (NMR) spectroscopy could help make this information quicker available and more accessible to researchers.

One-Step Contactless Check Weighing with TD-NMR

Contactless Check Weighing is traditionally a two-step process, but TD-NMR technology offers a much more convenient one-step solution. Learn more here.

TD-NMR can be used to Determine Different Formulations of Pasta

1H Low Resolution NMR proved to be an efficient technique to study and describe pasta structure and quality

TD-NMR can be used to Assess Phase Changes in Surfactant Solutions

Surfactants are amphiphilic molecules possessing both hydrophilic and hydrophobic portions. They are used to reduce the surface tension of a liquid.

Easy, Robust and Reproducible Solid Fat Content Analysis

The minispec TD-NMR system delivers simplicity and reproducibility and is the internationally recognized standard method.

Emulsions in the Petrochemical Industry

Bruker’s versatile and easy-to-use bench-top TD-NMR analyzer is a turn-key solution to measure unimodal droplet size distributions.

Analyzing electrode slurries to optimize cost of lithium-ion battery production using the Bruker minispec

Here we describe how the Bruker minispec Time Domain NMR (TD-NMR) spectrometer can measure critical physical properties of a slurry and allows manufacturers to optimize the coating process for lithium-ion batteries.

Time-Domain NMR Details Effects of Nanoparticles on The Micro-Fluidity of Heavy Oil

With ever-decreasing supplies of crude oil, the optimization of oil recovery techniques is of critical importance.

Using Time-Domain NMR to Determine Shelf Life of Products

Efficient and effective production and quality control procedures are critical and measuring oil and moisture content has become one of the most important concepts in the industry.

Time Domain-NMR Effectively Distinguishes Between Crystalline and Amorphous States in Powdered Tablet Formulations

Time Domain-NMR effectively distinguishes between crystalline and amorphous states in Powdered Tablet Formulations. Click here to learn more.

EarlySstages of Fat Crystallization Can Be Detected Using NMR

Early Stages of Fat Crystallization Can Be Detected Using NMR

The food industry uses vegetable fats as a key ingredient of numerous products.

Accessories

minispec Automation

A new sample automation system dedicated to minispec applications

Webinars

January 26, 2021

New Benchtop TD-NMR Solutions for Pharma and BioPharma

Bruker introduces ‘over the counter’ solutions for different pharmaceutical unmet needs such as phase purity, including quantification of low levels of amorphous, 100% fill check of vials and syringes and aggregation determination.

ON DEMAND SESSION - January 20, 2022

Solid Form Quantification of APIs with Benchtop TD-NMR – Form Check 2.0

Bruker introduces a new version of the minispec Form Check for quantification of polymorphs and amorphous form and invites Luca Venturi of Chiesi Farmaceutici to present his latest results which explore the boundaries of the method.

ON DEMAND

Droplet Size Analyzer 2.0. A TD-NMR Solution for Droplet Size Distribution in Food Emulsions

Droplet size distributions (DSDs) play a major role in the development of new products, influencing mouth feel, stability of emulsions, and shelf life. This webinar will present the Droplet Size Analyzer 2.0, an improved software solution for DSDs in food emulsions using minispec, a Bruker TD-NMR system. The new solution introduces a new user interface, GoScan for minispec, and improved data analysis including the calculation of multimodal droplet size distributions.

May 8, 2018

Solid Form Quantification – A New Benchtop Solution

TD-NMR is a non-invasive technique, ideal for the quantification of amorphous in the presence of crystalline form and/or excipients, with high accuracy, even when amorphous is present at low level.

LabScape

Service & Life Cycle Support for Magnetic Resonance and Preclinical Imaging

Bruker’s commitment to provide customers with unparalleled help throughout the buying cycle, from initial inquiry to evaluation, installation, and the lifetime of the instrument is now characterized by the LabScape service concept.

LabScape Maintenance Agreements, On-Site On-Demand and Enhance Your Lab are designed to offer a new approach to maintenance and service for the modern laboratory