The automated CellHesion® 300 is the ideal tool for measuring cell-cell, cell-tissue, and cell-substrate interactions with single-molecule sensitivity. It enables fast and easy measurement of the structure, morphology, and nanomechanical properties of living biological systems, delivering crucial insights into the role they play in various pathological disorders. This innovative system creates novel possibilities for applications in biophysics, biochemistry, implant research, wound healing, developmental biology, stem cell research, infection biology and immune response studies.
CellHesion 300 provides reproducible, quantitative data of unprecedented quality. Its high degree of automation increases throughput and delivers the productivity, performance, and statistical significance required for biomedical and clinical research environments. Important parameters, such as maximum adhesion force, individual unbinding events, and tether characteristics are automatically determined from each dataset by innovative software solutions.
Only CellHesion 300 delivers:
Prof. Dr. Ansgar Petersen
BIH, Center for Regenerative Therapies
Charité Medical University, Berlin, Germany
State-of-the-art software, intuitive user guidance, and automated alignment of the detection system provide the key to autonomous operation and fast results.
The new CellHesion 300 user interface gives the operator quick and easy control of the system and its operating parameters.
The software offers an easy-to-use scripting tool for user-defined experiments. Powerful batch data processing capabilities enable the analysis and quantification of large datasets at the touch of a button.
Discover the Possibilities
Mapping of the viscoelastic properties of samples with a large topography range, over an extended frequency scale with an optional Z-scanner and NestedScanner capabilities
Studying living cells under near-physiological conditions with an extensive range of accessories for control of environmental conditions, such as temperature and CO2 levels
Automate Investigation of Large Samples
The new SmartMapping feature enables the selection of flexible, user-defined 2D shaped force maps. The optimal range of force acquisition is continuously evaluated and automatically adjusted by new large-scaled Z-motors. Using optical tiling, multiple areas of interest can be selected in advance and automatically examined, allowing the easy and effective study of large sample areas. The improved motorized stage accuracy delivers a degree of precision and velocity second to none.
Integrate Seamlessly with Optical Microscopes
CellHesion 300 can be seamlessly integrated into the latest research grade optical microscopes with advanced and super-resolution capabilities, to deliver real-time, correlative data sets for the comprehensive characterization of living biological samples. Versatile experimental setups and automated adjustment
of system parameters opens new possibilities for long-term, self-regulating experiment series. CellHesion 300 is the ideal solution for the investigation of rough surfaces, densely packed cell layers, and highly corrugated tissue samples.
Bruker’s BioAFMs allow life science and biophysics researchers to further their investigations in the fields of cell mechanics and adhesion, mechanobiology, cell-cell and cell-surface interactions, cell dynamics, and cell morphology. We have collected a gallery of images demonstrating a few of these applications.
Optical systems/accessories, electrochemistry solutions, electrical sample characterization, environmental control options, software modules, temperature control, acoustic and vibration isolation solutions and more. Bruker provides you with the right accessories to control your sample conditions and to perform successful experiments.
Our webinars cover best practices, introduce new products, provide quick solutions to tricky questions, and offer ideas for new applications, modes, or techniques.