The Role of Small Molecule NMR in Medicinal Chemistry

Since its early days, nuclear magnetic resonance (NMR) has played an important role in the pharmaceutical industry. NMR is traditionally used by medicinal chemists for structure elucidation of both synthesized molecules and active compounds isolated from natural sources. However, it can also be a valuable tool for reaction monitoring, the characterization of solution conformations, the investigation of metabolites, hit-to-lead optimization and quantitation.

In this on-demand webinar, Kathleen Farley, Senior Principal Scientist, R&D, Pfizer Inc, describes how NMR spectroscopy is integrated into the Pfizer drug discovery pipeline and how the technique is used in a walk-up environment by medicinal chemists and NMR scientists to solve challenging drug discovery problems.

Additionally, Anna Codina, Director Pharmaceutical Business Unit, Bruker BioSpin, finishes the webinar by presenting new additions to the NMR instrumentation family that make the technique available to a wider audience, overcoming some of the current cost concerns. This expansion includes both affordable high-resolution and benchtop instrumentation.

Thursday 02 December 2021

04:00 PM CET