Clarity PET Reconstruction

Bruker Clarity PET Reconstruction is a new software toolset for advanced PET reconstruction powered by Bruker’s true DOI measurement detector technology. Bruker Clarity features state of the art algorithms, real time reconstruction and integrated advanced corrections, all fine-tuned as part of ready to use application specific imaging protocols or as user selectable.

Bruker Clarity’s exclusive algorithms run a GPU cluster for ultra-fast reconstructions. Bruker Clarity is the new advanced PET Reconstruction toolset within the ParaVision 360 ecosystem, and it unifies PET/CT and PET/MR workflows for operational excellence.

• Full‑FOV accuracy with true DOI technology delivers high‑resolution, fast PET images for multi‑animal and whole‑body scans under realistic lab conditions.
• Flexible reconstruction algorithms (MLEM, OSEM, FBP) enable the ideal speed‑to‑noise balance for low‑count studies and fine anatomical structures.
• Real‑time online reconstruction provides live feedback during acquisition on the scanner and in ParaVision Workplace, reducing failed scans and enabling immediate protocol adjustments.
• GPU‑accelerated performance completes standard reconstructions in ~2 minutes, fully quantitative attenuation‑corrected scans in ~4 minutes, and highest‑resolution MAP reconstructions in ~20 minutes.
• MAP is available for OSEM and MLEM with selectable priors (Quadratic & Total Variation) and a user selectable hyperparameter to allow high iterations yet keeping noise low.
• Integrated physical corrections (PSF, PVC, SSS scatter correction) deliver accurate SUVs and uptake values to strengthen quantitative confidence in publications and grant applications.
• Anatomy‑guided Bowsher Prior preserves small‑structure detail—especially critical for neuroimaging—while maintaining quantitative accuracy and ROI‑level confidence.

Accelerate reconstruction without compromising quality.

Achieve higher image fidelity and quantitative accuracy while dramatically speeding up reconstruction workflows and enabling real‑time decisions during acquisition.

The result is higher throughput, fewer re‑scans and failed sessions, lower operational costs, and reproducible, publication‑ready data. Faster cohort completion and improved consistency also support better 3Rs outcomes, with less handling and stress per animal.

• Video based experiment planning is faster than regular Scout View and safer for the animal as it avoids the X-ray dose

• Assess the biodistribution of your target radiotracer as the acquisition takes place. 
• Real-time decision-making based on list-mode reconstruction means you can rest assured that your injection went well or receive early information to decide whether to modify your study.

Fast reconstructions are achieved even with the highest quality settings enabled, thanks to:

• DOI-corrected list-mode data, eliminating the need for time-consuming modeling or simulations
• Highly efficient implementations of established reconstruction algorithms
• Multiple GPU acceleration

4 x GPU Cluster