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MALDI Biotyper® sirius System - the "sirius" solution for extended research capabilities for microbiology

Bruker, being a global leader in MALDI-TOF technology, continuously invests in development and improvement of its instrument portfolio. As a result, this new "sirius" member of the MALDI Biotyper family has been launched in the scope of broadening research capabilities, including resistance detection applications. 

Updated electronics | enabling further system improvements

  • Lighter: only 75 kg / 165 lbs
  • Faster target exchange
  • LED strip to remotely observe system status
  • Positive/negative ion mode 

The new Bruker MALDI Biotyper sirius comprises the widely appreciated high capacity vacuum system of the MALDI Biotyper smart, as well as its fast 200 Hz smartbeam™ lifetime* laser. 

 

Developments in the electronics have expanded the system’s capabilities to allow for positive and negative ion detection.

 

MALDI Biotyper sirius system

* Lifetime meaning 7 years or 500 million shots, whichever comes first

All inherited, improved and new features of the MALDI Biotyper sirius are held inside a true benchtop system of only 75 kg, allowing easy implementation in the lab. The system is fully compatible with existing MALDI Biotyper software, libraries and consumables for microbial identification and beyond.

Daily laboratory life has been simplified by an LED strip on the front housing, conveniently allowing a visual system status check from a remote place in the lab.

Positive/negative ion mode

Routine microbial identification is performed using positive ion mode only. The negative ion mode broadens the microbial research applications for the MALDI Biotyper sirius, such as the analysis of lipids.

An exciting new MALDI-TOF lipidomics research topic is the rapid detection of colistin resistance related modifications to lipid A in colistin-resistant bacteria such as Acinetobacter baumanii¹ or Escherichia coli².

Negative ion mode MALDI-TOF MS reveals the phosphoethanolamine modification of lipid A in colistin-resistant E. coli variants With courtesy from Gerald Larrouy-Maumus, Imperial College, London-UK
Negative ion mode MALDI-TOF MS reveals the phosphoethanolamine modification of lipid A in colistin-resistant E. coli variants
With courtesy from Gerald Larrouy-Maumus, Imperial College, London-UK
(click to enlarge)

To download the brochures click here: RUO brochure/ GP brochure.

¹Dortet L et al., 2018, Scientific Reports, Vol: 8, ISSN: 2045-2322
²Dortet L et al., 2018, Journal of Antimicrobial Chemotherapy, Vol: 73, Pages: 3359-3367, ISSN: 0305-7453

For research/general purpose use only. Not for use in clinical diagnostic procedures.