Ressonância Magnética

Soluções pesquisa clínica de NMR

A plataforma de caracterização metabólica de ressonância magnética nuclear (NMR) completamente estandardizada e totalmente automatizada é a tecnologia única e ideal de escolha para a análise de alto desempenho de fluidos corporais humanos, permitindo uma investigação metabolómica clínica eficaz e o desenvolvimento de ensaios relacionados (nível de utilização para investigação apenas)

Contact Support

Com a plataforma Bruker Avance IVDr, uma solução de triagem completamente estandardizada e totalmente automatizada, podem ser gerados dados de NMR de fluidos corporais humanos da mais alta qualidade e resultados analíticos sob procedimentos operacionais estandardizados.

As principais características da plataforma Bruker IVDr são as seguintes:

Preparação de amostras mínimas
Medição não destrutiva
Automação total na triagem de alto rendimento
A mais alta reprodutibilidade e qualidade de dados de amostra para amostra e de instrumento para instrumento
Quantificação altamente fiável de grandes conjuntos de metabolitos com relatórios automáticos
Classificação e discriminação através da utilização de ferramentas estatísticas com relatórios automatizados

Avance IVDr

High Throughput NMR for Development and Validation of High-Quality and Cost-Effective IVD-by-NMR research and pre-clinical in vitro Screening Assays.

Advanced Chemical Profiling 2.0

Data processing, interpretation, and automatic report generation are crucial steps in recurring tasks such as formulation screening within the chemical manufacturing industry. Bruker’s new Avance Chemical Profiling Modules simplifies these tasks.

Soluções

B.I. Methods

Highly standardized and fully automated NMR methods for high performance bodyfluid analysis at 600 MHz. Currently available for Urine, Plasma/Serum, CSF and Methanol extracts (of bodyfluids, cells or tissues)

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BBIOREFCODE

NMR community is enabled to get deeper insights in their samples through correct compound identification

B.I.QUANT-UR

Highly reliable and automated quantification of small molecule in Urine

B.I. Quant-PS

Highly reliable and automated quantification of small molecule in Plasma and Serum

B.I. LISA

Fast and reliable determination of Lipoprotein Subclasses and subfractions in Plasma or Serum

B.I. Biobanc QC

B.I. BioBank QC

Standardized and fully Automated Quality Control of incoming samples for storage in Biobanks

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B.I. IEM Panel

Support diagnostic interpretation of B.I.QUANT-UR for Inborn Errors of Metabolism

Avance IVDr Applications

All the NMR data and results generated with the standardized Bruker Avance IVDr platform are completely exchangeable between research groups worldwide and can be used for common data analysis.

Aplicações

Webinars

Discovery of small molecules that target RNA. NMR is the method of choice.

How To Evolve Your Biobank Business Model

In achieving research growth, today’s Biobanks face ever increasing challenges in the form of more precise and consistent quality control, the need for training and streamlining of operations to produce that quality control, and the need for new revenue streams to support these enhanced operations.

NMR International COVID-19 Research Network at Work

7 de jul. de 2021

NMR | COVID-19 | Research

In the current worldwide COVID-19 pandemic situation, fast developments not only in vaccines are needed, but also in analytical techniques to detect the infection, predict outcomes during hospitalization and more and more important towards Long COVID.

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New insight into dietary behaviour using NMR profiling

One of the big issues currently faced throughout the world is a rise in non-communicable diseases, such as obesity, type 2 diabetes, coronary heart

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February 12, 2020

NMR-based newborn screening for the detection of congenital metabolopathies (For Research Use Only)

Important Note: The methods and solutions discussed during the webinar are for research use only and not for use in clinical diagnostic procedures

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August 27, 2020

COVID-19: What’s NMR got to do with it?

We are living through a public health crisis the likes of which has not been seen for generations.

Solve the Identification of Unknown Compound in Body Fluids

Spectroscopic Techniques to Solve the Identification of Unknown Compound in Body Fluids (for research use only)

During the statistical analysis of spectroscopic data from bodyfluids (NMR and/or LC-MS) signals of compounds of unknown identity often occur.

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October 14, 2020

Urinary NMR Diagnostics for Inborn Errors of Metabolism Using Rule-based Interpretation (For Research Use Only)

Inborn errors of metabolism are rare diseases that often provide a typical pattern of elevated metabolites in biological fluids like urine

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Scientific On-Demand Webinars

Get free access to our most successful on-demand webinars grouped by application with just one login in our new digital content experience hub.

From biological Exploration to Clinical Translation: Lipoproteins in Inflammation Response

ON DEMAND SESSION - September 25, 2024

From biological Exploration to Clinical Translation: Lipoproteins in Inflammation Response

Recent studies highlight the importance of glycoproteins and lipoproteins in both acute and chronic inflammation. Notably, inflammation can alter the composition and influence the pro- or anti-inflammatory behaviour of HDL particles.

Testemunhos

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Metabolic Profiling & Screening Using Advanced NMR Technologies at CIC bioGUNE

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Setting up the Australian National Phenome Centre

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NMR in Metabolomics - Interview with Prof. Claudio Luchinat

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Opening of the IVDr lab in Luebeck, Germany

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Professor Jeremy Nicholson - Murdoch University

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Interview with Prof Matthias Nauck from University Greifswald, Gemany on IVDr by NMR

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