amaZon speed ETD Ion Trap

Desempenho inigualável de armadilha de íons para soluções de proteômica

O novo amaZon speed ETD incorpora invenções cruciais para oferecer recursos de proteômica sem precedentes. A alta abrangência dinâmica e complexidade das amostras proteômicas devido a modificações pós-translacionais exigem o máximo de velocidade e sensibilidade para capturar tantos peptídeos quanto possível.

A armadilha ETD de íons de velocidade amaZon estabelece novos padrões na identificação de proteínas, com sua maior velocidade de MS/MS, novo isolamento SWIFT e fragmentação SMART. Isso resulta em uma identificação de rotina sem ambiguidades de mais de 2500 proteínas em apenas uma sessão de LC-MS/MS de 5 µg de um lisado HeLa. A linha de transferência de funil de íon dual oferece sensibilidade de aferição absoluta.

Unmatched ion trap performance through innovation

  • Bottom-up proteomics identifying more low abundant proteins due to greatly increased MS/MS duty cycle
  • Top-down sequencing (TDS) for highest protein sequence coverage
  • Highest confidence through market leading mass accuracy
  • Leading dual ion funnel technology for unparalleled sensitivity
  • Outstanding ETD/PTR applications for full PTM analysis
  • New SMART isolation and fragmentation
  • Unrivalled scan speed of 52,000 u/sec at a peak width < 0.5 u for resolution of doubly charged ions

Applications amaZon speed ETD

High Sequence Coverage by CaptiveSpray™

The amaZon speed is equipped with the high-transmission, robust CaptiveSpray™ source for highest performance and reproducibility in bottom-up studies.

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Ultimate protein identification rates

Suvey view of a Hela cell digest (5µg) separated by a nano UHPLC and amaZon speed ETD equipped with a CaptiveSpray™ ion source.

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Market leading dynamic range

The amaZon speed ETD identifies proteins over at least 5 concentration levels  in a single run.

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Complete PTM characterization by Electron Transfer Dissociation (ETD)

Many proteins execute their molecular function by reversible posttranslational modifications (PTMs) like e.g. phosphorylation. The identification and unambiguous localization of the modification site is of major importance to understand the biological context. ETD preserves the modification of the peptide backbone and therefore allows the clear assignment of the modification site. The amaZon speed is the unrivalled performance leader by its market proven ETD technology: most sensitive, robust and reliable. 

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Bruker Daltonics services are performed by factory trained and certified engineers. DIN EN ISO 9001:2000 requirements are fulfilled.

 

Available services include:

  • Help desk service for a faster access to our support team, to your service order follow up and for general information
  • Planned maintenance, according to our requirement
  • Telephone support from highly-skilled troubleshooting professionals, to isolate and resolve hard- and software problems
  • Web-based remote instrument service for service diagnosis and applications support
  • Customer on-site repair and maintenance service
  • Spare parts availability typically over night or within a few working days worldwide
  • Compliance services for installation qualification, operational qualification / performance verification
  • Site planning and relocation
  • Advise to improve labs efficiency (consumable, method development & how to run the complete solution)

For Research Use Only. Not for Use in Clinical Diagnostic Procedures.