Insights on Biosimilars/Biologics through NMR Spectroscopy
21 - 22 November 2024,
Indian Institute of Technology Bombay, Powai, Mumbai
Pharma Knowledge Seminar
Insights on Biosimilars/Biologics through NMR spectroscopy
in collaboration with Indian Institute of Technology Bombay and Bruker Biospin.
What Awaits You:
- NMR in Biologics special focus on mAb analysis: Nuclear Magnetic Resonance (NMR) provides high-resolution insights into the higher-order structure (HOS) of mAbs, crucial for ensuring their stability and efficacy. This technique allows for detailed characterization at the atomic level, aiding in the development and quality control of biopharmaceuticals.
- NMR for drug receptor interaction: NMR is pivotal in studying drug-receptor interactions by providing detailed insights into the binding dynamics and structural changes at the atomic level. This technique aids in identifying and optimizing drug candidates by revealing how they interact with their target receptors.
- Complex injectables/Suspensions/Biphasic or gel formulations by ssNMR/HRMAS: Powerful techniques for analyzing complex injectables, suspensions, biphasic, or gel formulations. These methods provide detailed insights into the molecular structure, dynamics, and interactions within these formulations, crucial for understanding their stability, efficacy, and performance
- Usage of NMR methods on Drug conjugates (ADC/PDC): Unravel the mysteries of drug conjugates - those clever combinations that enhance drug effectiveness.
- NMR for continuous flow Bioproduction: Continuous flow bioproduction enables real-time monitoring and control of biochemical processes, providing detailed insights into reaction dynamics and component interactions. This technique enhances process efficiency and product quality by allowing precise adjustments during production
Panel Discussion:
Learn from our experts, who will guide you through real-world applications and case studies.
They’ll show you how NMR advances peptide and Biosimilar/biologics research.
Network and Collaborate:
Share experiences, discuss challenges, and explore potential collaborations.
Secure your spot now as seats are limited and embark on this exciting journey!
With Best Regards,
Your Bruker Team
Date: 21 - 22 November 2024
Time: 9:00 AM - 5:00 PM
Venue: Indian Institute of Technology Bombay
Main Gate Rd, IIT Area, Powai, Mumbai,
Maharashtra 400076
Seminar at: VMCC Auditorium
Agenda: Thursday, November 21, 2024
| Time | Duration | Topics | Presenters |
| 09:00 AM - 09:45 AM | 45 Min | Registration and Networking | |
| 09:45 AM - 09:55 AM | 10 Min | Opening Remarks and Vision | Mr. Jayant Nagavkar & Dr. Ashutosh Kumar |
| 09:55 AM - 10:40 AM | 45 Min | How can NMR contribute to the field of Biologics/Biosimilars | Prof. R. V. Hosur, IIT Mumbai |
| 10:40 AM - 11:25 AM | 45 Min | NMR for Contineous Flow Bioproduction | Dr. Victor Beaumont, Bruker |
| 11:25 AM - 11:45 AM | 20 Min | Tea / Coffee and Networking | |
| 11:45 AM - 12:30 PM | 45 Min | NMR in Biologics special Focus on mAb Analysis | Dr. Ashutosh Kumar, IIT Mumbai |
| 12:30 AM - 01:15 PM | 45 Min | PANEL DISCUSSION: Moderator - Dr. Ashutosh | Dr. Navaratna, Dr. Victor Beaumont & Dr. Neel Sarovar |
| Topic: Future Development in Biologics/Biosmilars though NMR Lens | |||
| 01:15 PM - 02:30 PM | 75 Min | Lunch Break | |
| 02:30 PM - 03:15 PM | 45 Min | Unveiling Protein-Ligand Dynamics and High-Order Structure Analysis with Mnova | Mr. Sandeep Baluni, Mestralab |
| 03:15 PM - 04:00 PM | 45 Min | 5WH Analysis of NMR in Biopharmaceutics | Dr. Amanth Chaterjee Cipla, Bengaluru |
| 04:00 PM - 04:40 PM | 40 Min | Hands-on experience of NMR | |
| Virtually Setting up an Experiments for Formulated Biopharma Drugs | |||
| Water Supression, HSQC, NOESY | |||
| 04:40 PM - 04:55 PM | 15 Min | Tea/Coffee Break | |
| 04:55 PM - 05:30 PM | 35 Min | NMR Lab Visit | |
| Setting up Experiments in 3 Parallel Groups | |||
Agenda: Friday November 22, 2024
| Time | Duration | Topics | Presenters |
| 09:15 AM - 10:00 AM | 45 Min | Innovation in Structural Biology - Benefits to the Biopharmaceutical Industry | Dr. Navaratna Vajpai, Biocon Biologics |
| 10:00 AM - 10:45 AM | 45 Min | Role of NMR in Biosimilars Assessment | Dr. Jithender Reddy, CSIR-IICT Hyderbad |
| 10:45 AM - 11:30 AM | 45 Min | NMR for Drug Receptor Interaction | Dr. Neel Sarovar Bhavesh ICGEB, Delhi |
| 11:30 AM - 11:45 AM | 15 Min | Tea / Coffee and Networking | |
| 11:45 AM - 12:30 PM | 45 Min | Bruker Focus on Pharma | Ms. Katherine Holab, Bruker |
| 12:30 AM - 01:15 PM | 45 Min | NMR Applications in the Development of Complex, Generic Injectables Drug Products: A Bird's Eye View | Dr. Sujoy Mukherji, Lupin Pune |
| 01:15 PM - 02:30 PM | 75 Min | Lunch Break | |
| 02:30 PM - 03:10 PM | 40 Min | PANEL DISCUSSION: Moderator - Dr. Abdur Rub | Dr. Sujoy, Dr. Jithender & Mr. Sandeep |
| Topic: Biopharma in the Era of AI | |||
| 03:10 PM - 04:15 PM | 65 Min | Hands on | |
| Data Processing | |||
| Genral Q&A | |||
| 04:15 PM - 04:30 PM | 15 Min | Tea/Coffee Break | |
| 04:30 PM - 05:00 PM | 30 Min | NMR Lab visit | |