Microbiology & Diagnostics

Microbiological Research

Identify and classify microorganisms for microbiological research and resistance testing

Microbiological Research

Understanding the epidemiology of various microorganisms is a key focus of microbiological research laboratories across the globe. Accurate and rapid microbial identification is vital for tracking the pathogenicity, virulence and antimicrobial resistance of strains and subspecies in the population, for clinical researchers as well as those in the food, veterinary, environmental and pharmaceutical industries.

State-of-the-art microorganism identification

Advanced technology, such as Matrix-Assisted Laser Desorption/Ionization Time-Of-Flight Mass Spectrometry (MALDI-TOF MS), is capable of identifying microorganisms to the species level, and classifying them based on their molecular fingerprint. Traditional sequence-based technologies cannot tackle the diversity of microorganisms that most microbiological research programs strive to examine.

MALDI-TOF MS provides microbial identification by matching the unique proteomic fingerprint of an unknown to an extensive library of reference spectra.

Custom libraries

In order for microbiological research libraries to benefit the community as a whole, they must be continuously updated to encompass as broad a range of species as possible. Although Bruker’s current reference library covers 3,239 species, thousands more are yet to be discovered. Microbiological researchers can optimize the microorganism classification process by creating, modifying and organizing reference spectrum data with an open library concept.

Sophisticated subtyping

Some genera are more challenging to differentiate than others, despite the power of MALDI-TOF MS. Subtyping, in addition to identification, facilitates the research of such organisms by providing unparalleled discriminatory power. By distinguishing between different strains or subspecies, researchers can track infectious disease outbreaks, monitor food pathogen outbreaks, and study sources of contamination in manufacturing processes, such as pharmaceutical production.

Related products

MALDI Biotyper® for Microbial Research

The MALDI Biotyper® (MBT) is a microbial identification system based on matrix-assisted laser desorption/ionization time-of-flight mass spectrometry (MALDI-TOF MS), allowing unbiased identification of microorganisms within a few minutes down to the species level. The MBT is an easy, rapid, robust, high-throughput, cost-effective and efficient identification technology, ideally suited to microbiological research laboratories.

Food & Beverage Microbiology

Accurate microbiological testing technology is vital for the detection of foodborne pathogens, possible food spoilage organisms and technological strains. Rapid identification and confirmation methods enable food and beverage manufacturers to make fast quality and safety decisions.

Water Testing Microbiology

Accurate identification of waterborne pathogens and quality indicators is key in microbial water testing.

Veterinary Microbiology

Among the current critical challenges facing veterinary microbiologists is the need to obtain secure species identification of rare and challenging organisms affecting animals, in a timely manner.

Pharmaceutical Microbiology

Pharmaceutical microbiologists are responsible for ensuring that the supply of life-saving drugs and vaccines are free from microorganism contamination. By maintaining product safety and quality with reliable microbial testing, the downtime of production and delay in deliveries can be minimized, while ensuring regulatory compliance. Pharmaceutical companies require microbial identification not only for production line control, but also for sterile products such as vaccines.