Packaging is an important component in the development of various drug formulations in the pharmaceutical industry. Packaging of pharmaceutical dosage forms has a close relationship between a pharmaceutical preparation and its package which is a major concern to the drug stability and safety.
In order to ensure quality control of final product, pharmaceutical companies employ the process of checkweighing, the ability to weighs items and provide highest weighing accuracy and repeatability. Contactless check weighing (CCW) is a non-destructive process already in use at Roche, using an established procedure for at-line process control for different vials and syringes using CCW to measure the filling weight of parenteral drug product solutions in vials and syringes. The pharmaceutical product is filled into syringes, vials or ampoules to a certain mass or volume, a quantity which has to be carefully controlled. The common method is weighing via a balance, which, for obvious reasons, is a two-step process. This in-package analysis is critical for pharma quality assurance purposes, pushing manufacturing efficiencies and delivering real-time data on process, product completeness and full compliance with cGMPs and regulations worldwide. This in-package analysis of products, without damage to the contents, enables the pharma company to avoid product wastage.