Speed - Robustness - Definition
Designed for MALDI Imaging
During the image acquisition the sample stage moves continually to achieve high pixel rates. The unique smartbeam 3D laser fires at a repetition rate of up to 10 kHz.
The smartbeam 3D laser features a laser diameter of 5 µm, enabling MALDI Imaging of tissue at 20 µm spatial resolution. As illustrated in the video, the laser can move independently from the sample stage to scan the full area of each pixel. This produces truly square pixels which utilizes the total available sample area for maximum sensitivity and pixel-to-pixel reproducibility.
Integrated software solutions
Leading Software for MALDI tissue typing
flexImaging allows to set up and analyze individual datasets
Integrating with SCiLS™ Lab Pro for statistical analysis allows automatic assignment of tissue classes.
With the unparalleled speed of the rapifleX®, 3D MALDI Tissuetyper® studies are within reach. The SCiLS™ Lab Premium 3D option allows the reconstruction, visualization, and statistical analysis of 3D Imaging datasets.
The speed of the rapifleX® Tissuetyper® allows for fast acquisition of images and SCiLS™ Lab solution seamlessly allows for classification of the data sets, enabling tissue typing at minimal time. Tissue micro arrays can be analyzed very rapidly. The soft smartbeam 3D laser effectively ionizes the analytes but does not harm the tissue, in fact histological staining is possible after the acquisition of the MALDI data set.
The combination of the mass spectrometric, molecular information with the histology of the analyzed tissue yields information-rich data sets, resulting in deeper understanding of the spatial distribution of molecules linked to the observed biology. The image displays a typical workflow, and also shows some statistical features of the SCiLS™ Lab solution
“Translational clinically oriented research with imaging mass spectrometry is critically dependent on speed and robust operation. Current instrumentation is limiting its full adaptation. The rapifleX MALDI Tissuetyper allows us to finally overcome that limitation. It enables us to engage in high-throughput clinical studies and establishes mass spectrometry imaging as a powerful and reliable information source for personalized medicine research.“
For Research Use Only. Not for use in clinical diagnostic procedures.