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Confocal Raman Microscope

RAMANwalk

The RAMANwalk is a confocal Raman microscope with a twist - an ingenious approach to Raman imaging that enables the generation of smart overview and preview images in minimal time and at high spectral quality.

Measure Smarter.    

Not Harder.

A Raman Microscope Driven by a More Intelligent Measurement Strategy.

Powered by stochastic sampling and high-speed galvano scanning, RAMANwalk continuously recognizes Raman patterns as they appear. The system automatically determines the most efficient measurement path, focusing on the regions that matter most and delivering Raman images more than five times faster than conventional scanning approaches.

Ease of use meets highest efficiency in Raman microscopy.

The RAMANwalk follows a new approach compared to traditional Raman microscopes - and that's why it stands out from the crowd. Highest spectral quality and super fast Raman image previews make it the perfect choice for routine.

The RAMANwalk offers:

  • Reduce imaging time by random-walk technology
  • Galvanic mirror for laser beam steering
  • High spectral and spatial resolution
  • Completely automated hardware
  • Powerful analysis for 2D/3D Raman images
  • Auto-calibration and auto-alignment
Demonstration of Laser Point Scanning.

The Best RAMANwalk Features and How They Help You.

Intelligent
The smartest path to Raman images.
RAMANwalk's Random Walk technology analyzes data as it is collected. When distinctive Raman patterns are detected, the system automatically adapts the measurement strategy to gather the most valuable information with maximum efficiency.
Practical
Quick to start. Easy to use.
RAMANwalk provides an efficient path from analytical question to meaningful Raman information. Straightforward workflows minimize unnecessary steps, helping users handle different samples and applications without adding complexity to the measurement process.
Accessible
Smarter Raman imaging for everyone.
Automated instrument calibration and alignment make RAMANwalk approachable for users with different levels of Raman experience. Users can focus on the sample and the result rather than managing complex instrument settings.
    

Comparing laser point scanning to "table" or raster scanning.

Conventional Raman microscopes typically follow a predefined raster pattern. RAMANwalk takes another route. Galvanic mirrors move the laser rapidly across the sample, while its Random Walk approach actively searches for Raman signals using chemical rather than purely visual information.

Once a Raman signal is identified, RAMANwalk investigates the surrounding area. When that signal disappears, the system reduces the probability assigned to the region and rapidly explores elsewhere. The result is a smarter route through the sample and exceptionally fast Raman preview images.

Conventional "meandering" table scanning compared to a random scan approach. Same number of tiles were measured, however, random scanning already collected the complete chemical information of the sample.
    

See meaningful Raman information sooner

RAMANwalk’s Random Scanning generates an early chemical preview by acquiring Raman spectra at distributed positions across the sample. These measured spectra provide the spectroscopic basis for estimating the information between sampled positions and constructing an interpolated Raman image.

As acquisition progresses, interpolated information is replaced by directly measured Raman data, allowing users to assess relevant chemical and spatial features before the complete measurement is available.

RAMANwalk microscope with laser class 1 safety housing.

Differentiate visually similar polymers

Polystyrene and PMMA beads are difficult to distinguish in the visual image. Raman imaging differentiates the polymers through their characteristic spectra and maps polystyrene in green and PMMA in purple. The interpolated image after 10 minutes already reproduces the main chemical and spatial features of the completed 23-minute measurement. This gives users an earlier overview of the sample while the acquisition continues.

Interpolated Raman image after 10 minutes compared with the completed image after 23 minutes. The preview already reproduces the principal distribution of the color-coded polymer components, while the enlarged region compares uninterpolated, interpolated and directly measured data.

Locate minerals of interest in complex ore samples

Raman spectroscopy identifies minerals through their characteristic vibrational spectra, providing information that complements elemental analysis. In this heterogeneous ore sample, the color-coded Raman image reveals the distribution and spatial associations of different mineral phases. The interpolated seven-minute image already indicates regions where the target mineral occurs, compared with the completed 20-minute measurement. This can support mineral exploration, ore characterization and decisions about further analysis.

Interpolated Raman mineral map after seven minutes compared with the completed 20-minute measurement. The preview already reveals the principal distribution and associations of the color-coded mineral phases, including the region containing the target mineral.

Visualize ingredient distribution in pharmaceutical formulations

Raman imaging differentiates pharmaceutical ingredients through their characteristic spectra and maps their distribution within a formulation. In this tablet, caffeine is highlighted in red alongside other components shown in green and blue. The interpolated six-minute image already reveals the principal caffeine distribution, compared with the completed 30-minute measurement. Such chemical images can support formulation development and the assessment of ingredient distribution, domain size and agglomeration.

Interpolated Raman image of a pharmaceutical tablet after six minutes compared with the completed 30-minute image. Caffeine is highlighted in red, enabling its distribution within the multicomponent formulation to be assessed before completion of the measurement.

Raman imaging applications.

RAMANwalk specifications.

Spatial Resolution350 nm in X and Y; 1 µm in Z
 
Objective Lenses5x, 10x, 20x, 50x, 100x 
Spectral Resolution<1.5 cm-1 (depends on grating, up to 3 gratings available)
 
Stage Details30 * 30 * 35 mm XYZ-motorized stage 
Calibration
Auto-calibration based on standard lamp and sample 
AlignmentAuto-alignment of optical path 
Laser SafetyLaser safety class I door with interlock