Bruker
A Different Approach to Raman Imaging

The Nanophoton Technology

Most Raman microscopes generate images through stepwise stage movement. Nanophoton takes a different approach. Using galvano scanning to control the laser beam, Nanophoton systems enable innovative imaging modes and more efficient acquisition of chemical images.

A Different Raman Imaging Strategy

Traditional Raman imaging relies on moving the sample step-by-step beneath a stationary laser beam. While effective, this approach can limit imaging speed and flexibility.

Nanophoton combines high-speed galvanometer scanning with precision motorized stage positioning. Within the microscope field of view, galvanometer mirrors rapidly steer the laser beam across the sample, while the stage moves only when larger measurement areas need to be covered.

This combination enables efficient acquisition of chemical images while supporting a range of imaging strategies, from rapid overview measurements to high-resolution Raman imaging.

Optical scanning provides rapid positioning within the field of view, while stage movement extends the accessible measurement area.

RAMANtouch and RAMANwalk use this architecture in different ways. Both support Galvo-Scanning and Random Scanning; RAMANtouch additionally uses Line Imaging and AreaFlash™.

In a stage scan, the measurement position changes by mechanically translating the sample. With Galvo-Scanning, the laser is repositioned optically instead.

The two approaches complement each other: Galvo-Scanning handles local acquisition within the optical scan field, while the motorized stage extends measurements to larger areas.

The Engine Behind Nanophoton’s Speed

Galvo-Scanning uses precisely controlled mirrors to steer the excitation laser across the sample. In Raman microscopy, this means the measurement position can be changed optically within the field of view instead of moving the sample stage from point to point.

That changes more than acquisition speed. Because the laser can be positioned rapidly and in different spatial patterns, the measurement no longer has to follow a conventional sequential raster scan.

This enables different Raman acquisition modes:

Galvo-Scanning

A focused laser spot is moved across the sample by galvanometer mirrors. A Raman spectrum is acquired at each selected position.

Line Imaging

A laser line excites multiple positions simultaneously, allowing Raman information from many spatial positions to be recorded in one exposure.

Random Scanning

Measurement positions are selected using Raman information already acquired from the sample. This allows chemically relevant regions to be identified without first completing a full raster scan.

AreaFlash™

A laser line is scanned across a defined area to obtain Raman information representative of that area rather than of a single measurement point.
 

 Galvanometer ScanningTraditional Table Scanning
SpeedMillisecond-level laser movementSlower mechanical positioning
Vibration / DriftNone (no sample movement)Potential vibration and drift
Scan ModesPoint, Line, AreaPoint, 3D
PrecisionSub-micron laser positioningLimited by stage mechanics
FlexibilityCombines with stage scanning when neededStage-only in most systems

The Story of Nanophon

A History Worth Repeating

Nanophoton’s story began in 2003 as a venture from Osaka University led by Professor Satoshi Kawata, a pioneer in photonics and microscopy. The young company set out with the bold mission to create “A Scientist’s Company.” From the very beginning and continuing to this day, Nanophoton’s engineers and sales staff have worked closely with universities and industrial labs to develop unique and original products.

In 2005, Nanophoton delivered breakthrough technology almost immediately by introducing the RAMAN-11 – the world's first laser-scanning confocal Raman microscope. This breakthrough was quickly recognized, as rapid market success validated Nanophoton’s technology and built trust among scientists and companies in Japan.

By 2006, Nanophoton had won the Japan Venture Award, and in 2007, the company leader Professor Kawata was honored with the Emperor’s Purple Ribbon Medal, a prestigious national award in Japan, for his remarkable professional accomplishments. Over the next decade, the company continued releasing new systems, quietly but steadily growing its reputation in both academia and industry.

In 2011, Nanophoton released the first generation of its flagship confocal Raman microscope, the RAMANtouch, which featured its most advanced imaging design to date. A patented line-shaped laser illumination combined with a fast galvanometer scanner, allowing the capture of hundreds of spectra simultaneously in a single scan. This design made imaging extraordinarily fast and reduced measurement time by a factor of several hundred.

This allowed researchers to acquire large-area chemical maps of a sample in minutes rather than hours, giving them rapid, high-resolution data. Building on this success and continually refining its technology, more specialized instruments followed: in 2016, the RAMANdrive for 300 mm semiconductor wafer inspection was launched, and in 2018, a deep-UV Raman microscope (RAMANtouch vioLa) for advanced photonics research was introduced.

Nanophoton Today

Today, researchers in materials science, electronics, batteries, polymers, and pharmaceuticals use Nanophoton microscopes for tasks such as plotting active ingredients and excipients in pharmaceutical tablets, analyzing 2D materials, and even exploring the secrets behind tasty chocolate by imaging its fat content. The company’s focus on user-driven solutions and patented technology has earned it strong support from customers, especially in Japan and Korea.

Many of these customers are global science and industry leaders. Companies such as Sony, Hitachi, and Panasonic, as well as Japan’s energy giant ENEOS, employ Nanophoton microscopes for product development and quality control. In advanced materials and device innovation, Samsung Electronics relies on Nanophoton for its imaging needs. LG Chem, a leader in battery and energy storage technology, uses Nanophoton’s systems to analyze materials critical to the next generation of energy solutions.

In the chemical and pharmaceutical fields, FUJIFILM integrates Nanophoton’s imaging technologies into its polymer materials research. Semiconductor manufacturing leaders such as SK Materials, SK On, and FST utilize Nanophoton’s solutions for their processes. Even global consumer tech innovator Dyson and Korean food and bioscience company Daesang turn to Nanophoton for their specialized research requirements. This diverse customer base testifies to the broad acceptance and trust Nanophoton has earned across sectors.

Beyond industry, Nanophoton’s instruments have become indispensable to many of Asia’s top academic and research institutions. Prestigious universities such as The University of Tokyo, Kyoto University, Osaka University, and Tohoku University, along with national research institutions like RIKEN, collaborate with Nanophoton on pioneering studies in materials science, chemistry, and life sciences. These collaborations have resulted in thousands of published journal papers.

A New Chapter with Bruker

 

After two decades of steady growth, product innovation, and trusted service in Japan and Asia, Nanophoton took a strategic step in 2024 by merging with Bruker. Today, as "Nanophoton – a Bruker Company", the combined strengths allow customers worldwide to benefit from the unmatched speed, sensitivity, and spatial resolution of Nanophoton’s confocal Raman microscopes, now backed by Bruker’s extensive global support network.

The famed  instruments, acclaimed by leading corporations and top universities across Japan and Asia, are now available on an even broader scale.

The IR and Raman Imaging Center

Professor Satoshi Kawata.
Bruker Optics President Andreas Kamlowski.
LUMOS II and Nanophoton RAMANtouch.

On May 8, 2025, the Bruker–Nanophoton Raman-IR Imaging Center officially opened in Toranomon, Tokyo.

Formerly Nanophoton’s Tokyo showroom, the renovated and expanded facility now showcases state-of-the-art Raman and infrared microscopes — likely the only place worldwide where both technologies can be experienced side by side for advanced materials research.

The opening ceremony featured remarks from Andreas Kamlowski (President, Bruker Optics), Christian Werner (VP Global Sales, Bruker Optics), Shigeru Shimada (Head of Bruker Japan Optics), and Professor Satoshi Kawata, Nanophoton’s founder and Chief Scientific Officer. Presentations followed from Taikan Minamoto on Nanophoton’s Raman microscopes and from Shimada on Bruker’s infrared systems. Live demonstrations and a networking reception completed the event.

The center symbolizes the merger of Nanophoton and Bruker, bringing together two pioneers in Raman and infrared microscopy. Professor Kawata emphasized that scientific and organizational barriers — between disciplines such as physics, chemistry, and engineering, or between corporate silos — often hinder innovation. The collaboration aims to break down these walls and foster a more integrated, transdisciplinary approach to research and development.

The merger was described as a partnership of equals: while Nanophoton is now legally part of Bruker, its brand, logo, and product names remain unchanged. A new design element — a subtle Bruker-blue line added to Nanophoton’s signature white instruments — symbolizes this union.

With the launch of the Raman-IR Imaging Center, Bruker and Nanophoton seek to provide researchers with an open, collaborative space and to accelerate innovation in advanced materials science worldwide.