Poster Hall Metabolomics

Poster Hall Metabolomics and Lipidomics

Posterhall Metabolomics and Lipidomics

The research field metabolomics aims at a comprehensive qualitative and quantitative analysis of all small molecules present in a cell, a tissue or even a whole organism. Responding to intrinsic or extrinsic triggers, the entirety of compounds will change. And the goal of studying these responses is to get a more holistic picture to understand e.g. the emergence and progression of diseases.

 

The lipidome can be considered a subset of the metabolome, covering all lipophilic compounds. Many lipids play important roles for example in cell communication and are associated with metabolic diseases. The similarity in the physical properties of lipids, despite their structural diversity demands for dedicated workflow solutions. These are different compared to classical metabolomics approaches. Both applications are supported in MetaboScape and both are facilitated by the additional dimension that is achieved using Trapped Ion Mobility Spectrometry (TIMS).

 

This poster hall shows a unique collection of investigations that leverage Bruker technology, e.g. showing the benefit of CCS values and the PASEF acquisition mode. We are very thankful to everybody who contributed their research results.

 

And we hope you enjoy reading through this poster hall as much as we enjoyed putting it together.

Poster Hall Metabolomics and Lipidomics

4D-Metabolomics

Poster IMSC 2022: Applying Trapped Ion Mobility Spectrometry (TIMS) for Vitamin D Epimer Differentiation

Poster IMSC 2022: Enhanced 4D workflows using TIMS for advancing small molecule research

Poster IMSC 2022: CCS-enabled timsTOF Pro PASEF workflow for in vitro human liver microsome drug metabolites profiling and characterization

Poster IMSC 2022: High resolution ion mobility timsTOF Pro for the fast separation and characterization of isomeric bile acids

Poster IMSC 2022: A Non-targeted 4D-Metabolomics Workflow for Quality Control of Chiral Heparin Disaccharide by LC-timsTOF and MetaboScape®

Poster 2021: CCS Predict Pro

Poster 2021: MetaboScape 2022 for core labs

Poster 2020: 4-dimensional annotation of Metabolomics features: CCS values as an additional source for higher confidence 

Poster 2020: Untargeted UHLC-HR-QTOF-MS metabolomics study to unravel metabolites contrlling wood formation in aspen trees 

Poster 2020: Integrating MetaboScape and PollyTM for the analysis of LC-TIMS-MS and LC-MS based fluxomics 

Poster 2020: Inlet Probe Coupled to Trapped Ion Mobility Time-of-Flight Mass Spectrometry

Poster 2019: Integrating 4D peak picking of LC-TIMS-MS/MS data into GNPS feature based molecular networking for metabolomics and lipidomics analysis 

Poster 2019: Integrated workflow with quality control for large cohort and clinical metabolomics research using robust hardware and signal correction 

Poster 2019: Development of a Collision Cross Section Library using Trapped Ion Mobility Spectrometry (TIMS) and Its Use in Plant Metabolomics 

Poster 2019: Enabling Rapid and High-confidence Metabolite Identification using HILIC-QTOF based MS/MS-RT library 

Poster 2019: Integration of metabolomic and lipidomic workflows for studying biological samples

 

For Research Use Only. Not for use in clinical diagnostic procedures.