Potency Determination by qNMR
During this webinar, Fabrice and Anna will introduce you to Bruker’s newly launched PotencyMR, a solution specially designed to facilitate potency/purity determination. You will also have an update on the existing tools for absolute concentration determination using an external reference. A full automatic workflow from sample submission to report will be shown which includes the measurement of replicate samples. You will see how challenging samples (formulated material) are also analyzed, in manual mode, and how this manual analysis can be stored for further reuse.
They will describe the NMR hardware that is best suited for Bruker’s qNMR and show how that complements LC methods in a very cost effective way. Example data and practical cases at 300 and 500 MHz will be shown.
All along the webinar key benefits of PotencyMR, such as ease of use and review, that make the solution accessible to non-NMR experts, will be highlighted, demonstrating that the deployment of qNMR to an open access environment is now a reality.
What you will discover
This webinar will explain how Bruker’s new PotencyMR solution streamlines potency/purity determination.
Key topics include:
- Introduction to internal and external standard qNMR methods
- Hardware description (300 and 400 MHz NMR)
- Demonstration of full automatic workflows for potency and absolute concentration determination
- How to measure replicate samples in automation
- Analysis of challenging samples in manual mode
After her post-doc she worked in the Analytical R&D department of Pfizer, UK, for 8 years, becoming proficient in low level impurity structure elucidation, reaction monitoring, qNMR and the preparation of regulatory documentation.
She joined Bruker in 2011 as Material Characterisation Laboratory Manager. Since then her role has evolved. She started looking after the pharmaceutical market in 2015 as Product Portfolio Manager. Anna and team launched several products: InsightMR, InsightXpress and InsighCell for process understanding and monitoring; Fragment Based Screening analysis tools, PotencyMR for potency determination of drugs by qNMR; the minispec Form Check for solid form quantification and NMR Instrument Qualification packages to facilitate compliance. She is now director of the pharmaceutical business Unit at Bruker BioSpin.