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The study of any biofluids as unique substances in each of us tiles the way for a revolution in the personalized cure, diseases prevention, allowing for early diagnosis and increasingly targeted pharmacological treatments.
Resolution in a new dimension for solving challenges of society
The new GHz-class NMR technology is now enabling novel research in functional structural biology of proteins and protein complexes.
Metabolomics Research - an Insight
Metabolomics Research at Uni Tübingen and Uni Lübeck:
We interviewed different Metabolomics research institutes to find out more about their research, daily work and latest findings.
High-field NMR and global collaboration drive Covid-19 protein research at Göttingen
As part of a 50-strong international collaboration of NMR experts, a team led by Prof. Dr. Markus Zweckstetter at the Max Planck Institute for Biophysical Chemistry in Göttingen, Germany, has been uncovering insights into the hidden workings of Covid-19. Using one of only a few 1.2 GHz NMR instruments in the world, his team is helping to elucidate the structure and interactions of the nucleocapsid protein within the SARS-CoV-2 virus and in doing so, identify promising options for drug targets.
Israeli scientists collaborate to speed up Covid-19 RNA research using ultra-sensitive NMR techniques
As part of an international collaboration of NMR experts, a team led by Professor Lucio Frydman at the Weizmann Institute of Science, Israel, has been helping elucidate the RNA structure of Covid-19. By using sensitivity-enhancing techniques such as nuclear hyperpolarization and magnetization transfer, the team has been able to obtain insights into both the primary and secondary structures of key RNA fragments – information that should ultimately enable pharmaceutical researchers to take a step closer to discovering effective drugs.
Using AI to speed up NMR-based protein structure determination
Prof. Dr. Roland Riek, based at ETH Zürich in Switzerland, has a broad range of research interests, most of which involve the application of NMR to biological systems, and proteins in particular. But his latest project is rather different from the rest, due to its focus on how to accelerate structure determination itself, using artificial intelligence (AI) to streamline the processes of NMR data acquisition and analysis.
Paramagnetic Resonance: A Rising Star in Battery Research Methods
An interview with Hu Bingwen, researcher at East China Normal University
NMR-based metabolomics: Making "precision medicine" a reality
What insights can NMR-based metabolomics provide into how cancer operates, and how therapeutic approaches might be tailored to the individual? We talk to Prof. Tone Frost Bathen about why she has valued NMR throughout her research career.
Personalized nutrition: The role of NMR in understanding human metabolism
Could individually tailored diets help improve health outcomes for people with diabetes, hypertension, and other chronic diseases? Prof. Elaine Holmes believes they can. With the help of nuclear magnetic resonance (NMR), she can obtain a molecule-level understanding of the differences in the way people metabolize food.
Bringing the power of NMR to everyday healthcare
Can nuclear magnetic resonance (NMR) play a more visible role in tackling the health challenges found in today’s society? Prof. Dr. Ulrich Günther believes it can, and that prospects are looking particularly strong in the field of personalized medicine.
The detection of air pollution through Environmentally Persistent Free Radicals (EPFRs)
In recent years, more attention has been placed on air pollution as it is increasingly becoming an invisible killer. But which type of particulate matter is most harmful to human health, and why? This is a subject that has confounded scientists and researchers for decades.
Demystifying diseases: Using NMR to understand Covid-19 at the molecular level
With Covid-19 set to remain a global health issue for years to come, understanding the molecular machinery of the SARS-CoV-2 virus and devising new strategies to prevent it working remain high on the research agenda. As a member of the Covid-19 nuclear magnetic resonance (NMR) Consortium, Professor Dr. Teresa Carlomagno is at the forefront of this effort, and here she explains to us why the capabilities of NMR give it a special role in the biochemist’s toolkit.
Moving metabolomics up a gear: Enhanced international collaboration enabled by NMR
To gain statistical significance from metabolomic studies of human diseases, you need a large cohort of patients willing and able to take part in medical studies – and an instrument that’s able to handle small volumes of samples and provide quantitative and reproducible analyte concentrations. Dr. Christoph Trautwein at the University of Tübingen, Germany, has been able to address both issues, thanks to the power of nuclear magnetic resonance (NMR). We talk to him about his work.
イタリア・フィレンツェ大学CERMのLucia Banci教授率いるチームは、50人以上のNMR専門家からなる国際的な協力体制のもと、SARS-CoV-2タンパク質の構造決定に貢献しています。 最近、ブルカー社の1.2GHz NMR装置を導入したことにより、原子レベルでの相互作用に関する詳細な情報が得られるようになり、創薬設計や最適化、SARS-CoV-2に対する抗体検証、バイオ医薬品の高次構造（HOS）に対する革新的なアプローチの開発に貢献できるようになりました。
How one of Spain’s most significant wine testing laboratories is using nuclear magnetic resonance to protect the industry
The Estación Enológica de Haro (EEH), located in the La Rioja region of Spain, is an oenological station belonging to the Government of La Rioja. Since its inception in 1892, the laboratory has become one of the country’s most significant wine testing facilities, using the latest technology to analyze Spanish wines. The EEH uses nuclear magnetic resonance (NMR) to obtain insights to quickly determine the origin and constituents in a wine sample. This in turn is helping to tackle the widespread demand for food safety and product certification. Here, Elena Melendez Alvarez and Eva Lopez Rituerto discuss their roles at the EEH and the work they carry out at the oenological station.
Bruker’s Benchtops for Education – How to Offer Hands-On NMR and EPR Experience to Students
Bruker has reimagined high-performance NMR and EPR spectroscopy in a compact and cost-efficient form to allow students hands-on experience.
What if NMR was easy? – Aspects, Attributes & Applications of the Fourier 80 FT-NMR benchtop spectrometer
Bruker has reimagined high-performance NMR spectroscopy in a compact, cost-efficient and straightforward form: the Fourier 80 FT-NMR benchtop
Collaboration in Science Like in The COVID-19 Pandemic - a model for the future?
Understanding the structure of the SARS-CoV-2 virus through collaboration in NMR analysis holds the key to finding a treatment.