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Markus Z NMR

High-field NMR and global collaboration drive Covid-19 protein research at Göttingen

As part of a 50-strong international collaboration of NMR experts, a team led by Prof. Dr. Markus Zweckstetter at the Max Planck Institute for Biophysical Chemistry in Göttingen, Germany, has been uncovering insights into the hidden workings of Covid-19. Using one of only a few 1.2 GHz NMR instruments in the world, his team is helping to elucidate the structure and interactions of the nucleocapsid protein within the SARS-CoV-2 virus and in doing so, identify promising options for drug targets.

Israeli scientists collaborate to speed up Covid-19 RNA research using ultra-sensitive NMR techniques

As part of an international collaboration of NMR experts, a team led by Professor Lucio Frydman at the Weizmann Institute of Science, Israel, has been helping elucidate the RNA structure of Covid-19. By using sensitivity-enhancing techniques such as nuclear hyperpolarization and magnetization transfer, the team has been able to obtain insights into both the primary and secondary structures of key RNA fragments – information that should ultimately enable pharmaceutical researchers to take a step closer to discovering effective drugs.
1.2 GHz bruker Spectrometer ETH Zürich

Using AI to speed up NMR-based protein structure determination

Prof. Dr. Roland Riek, based at ETH Zürich in Switzerland, has a broad range of research interests, most of which involve the application of NMR to biological systems, and proteins in particular. But his latest project is rather different from the rest, due to its focus on how to accelerate structure determination itself, using artificial intelligence (AI) to streamline the processes of NMR data acquisition and analysis.

Paramagnetic Resonance: A Rising Star in Battery Research Methods

An interview with Hu Bingwen, researcher at East China Normal University