Pharma Content Collection
Precision Workflows in Pharma and Biopharma with Bruker
In the rapidly evolving landscape of pharmaceutical research and development, speed and precision are paramount. At Bruker, we understand the critical need for advanced analytical tools that not only accelerate the drug discovery process but also enhance the accuracy and reliability of your findings. Our state-of-the-art mass spectrometry solutions, including Trapped Ion Mobility Spectrometry (TIMS), Matrix-Assisted Laser Desorption/Ionization (MALDI), and Magnetic Resonance Mass Spectrometry (MRMS), are designed to meet these demands, providing unparalleled capabilities for comprehensive multiomics profiling, spatial analysis, and accurate compound identification.
Launch Material for timsOmni™, timsMetabo™, timsUltra AIP, proteoElute™
GlycoTyper/GlycoTyper Pharma
- GlycoTyper Page
- LCMS 242 - From Spatial Biology Glycomic Imaging to High Resolution Glycoproteomics: Integrating GlycoPath MALDI-MSI and glyco-PASEF Glycopeptide LC-MS/MS
- MT 146 - N-glycan profiling of biotherapeutic monoclonal antibodies using Bruker’s timsTOF fleX and neofleX platforms and BioPharma Compass Software: a novel tool for smart lead development and selection in pharma-biotech R&D
Biologics
- OmniScape Page
- Brochure OmniScape - A New Era of Confidence in Top-Down Sequence Analysis
- Brochure maXis II for BioPharma Analysis
- Brochure BioPharma Compass - Accelerate Routine BioPharma Characterization
- MT 143 Rapid automated analysis of oligonucleotides and peptides using the neofleX platform
- MT 142 - A Novel Top-Down Protein Sequencing Workflow Employing neofleX Benchtop MALDI-TOF/TOF and OmniScape Software
- PN 66 - Lipid Nanoparticle Component Analysis by MALDI Using timsTOF fleX
- LCMS 227 - Intact mAb analysis on the timsTOF HT QTOF mass spectrometer with BioPharma Compass
- LCMS 217 - Optimized liquid chromatography mass spectrometry methods for intact protein analysis and peptide mapping of adeno-associated virus capsid proteins
- LCMS 215 - OligoQuest: Oligonucleotide purity analysis with side-product identification and quantitation
- LCMS 209 - 4D analysis of lipid nanoparticles using Elute-timsTOF Pro 2 with VIP-HESI
- LCMS 204 - Oligonucleotide characterization with a timsTOF Pro 2 QTOF mass spectrometer and the OligoQuest workflow of the BioPharma Compass software
- LCMS 200 - Complete characterization of a 15 kDa nanobody by TIMS-enabled Next-Generation MALDI Top-Down Sequencing
Spatial Biology
Ultra Sensitivity
- CaptiveSpray Page
- Immunopeptidomics Page
- Brochure - timsTOF Ultra 2
- LCMS 226 - High sensitivity class I immunopeptidomics on the timsTOF Ultra mass spectrometer
- LCMS 205 - PaSER Novor: Real-time de novo sequencing for 4D-Proteomics applications
- LCMS 203 - High sensitivity class I immunopeptidomics on the timsTOF SCP mass spectrometer
Omics at Scale
- GlycoScape Page
- Targeted Protein Degraders Page
- ProteoScape Page
- Lipidomics Page
- Brochure - TwinScape
- Brochure - timsTOF HT
- LCMS 223 - Low-variation proteome profiling across 10 labs, identifying 7200+ protein groups in 5 minutes with dia-PASEF
- LCMS 219 - Improving off-target liability assessments with a dia-PASEF workflow for competitive Activity-Based Proteomics Profiling (cABPP)
- FN 28 - TwinScape: a digital twin-driven solution for quality management in the modern proteomics laboratory
High-throughput Screening
- Brochure - timsTOF MALDI PharmaPulse Automation
- LCMS 225 - Assessing site-specific structural changes in monoclonal antibodies utilizing Covalent Labeling Mass Spectrometry (CL-MS)
- LCMS 216 - Next-Level Performance in Label-Free High-Throughput Screening of Protein-Ligand Interactions with timsTOF MALDI PharmaPulse
- MT 129 - Label-free drug uptake analysis of whole cells by MALDI-TOF mass spectrometry using the transport protein OATP2B1 as an example
For Research Use Only. Not for use in clinical diagnostic procedures.