Live from the Lab: Spatial proteomics in action
Overview
Spatial proteomics, which enables spatially and cell-type resolved protein profiling in tissue specimens, is the Nature Methods Method of the Year 2024. A particularly powerful methodology is the integration of advanced imaging with exploratory liquid chromatography-mass spectrometry (LC-MS) based proteomics. Current workflows allow the profiling of a few cells, such as cellular niches, and even single cell applications.
With such high-resolution methods, increasing sample throughput is essential and requires robust, reproducible, and scalable LC-MS workflows to cope with these demands.
In this webinar, learn from the experts in the field about:
- Image processing and region co-registration for laser microdissection (LMD)
- Sample capture and sample preparation
- Proteome analysis on the Evosep Eno and timsUltra AIP, enabling a "100 spatial proteomes a day" workflow
Speakers
Melissa Klingeberg, Ph.D. Candidate, Coscia Lab, Max Delbrück Center for Molecular Medicine, Berlin, Germany
Jose Nimo, Ph.D. Candidate, Coscia Lab, Max Delbrück Center for Molecular Medicine, Berlin, Germany
Christoph Krisp, Ph.D., Application Development Specialist Single Cell Proteomics, MDC-Bruker Center of Excellence for Single Cell Omics, Berlin, Germany
For Research Use Only. Not for use in clinical diagnostic procedures.