Pharma enews 2020 july
Topic 1 enews september 9 2020

Developments and Emerging Trends in Solid-State NMR of Pharmaceuticals

In this article Dr. Frederic G. Vogt highlights the use of SSNMR for the observation of hydrogen bonding, especially relevant when studying pharmaceutical cocrystals and discusses the technique’s capability of obtaining structural information from amorphous solid dispersions, currently widely used in drug delivery. Read more

Topic 2 enews september 9 2020

Future Laboratory Informatics (FLI)

Online Event September 15 - 17, 2020: Industry focused discussions on the challenges and opportunities presented by future informatics technologies, and the best-in-industry strategies to implement for effective data management and compliance alongside your laboratory’s digital transformation programmes.

On September 15, 1 pm (GMT) Jeff Carter, Co-founder and COO, Arxspan (a Bruker company) will talk about: Building An Integrated End-to-End Solution for Analytical Labs.

  • Assess effective ways to integrate analytical requests, data acquisition and approval work flows
  • li>Automated retrieval, analysis and publication of results data to streamline your operations
  • Build processes to ensure a fully integrated ELN, sample processing workflow, compound registration and inventory

Read more

Topic 3 enews september 9 2020

1H, 13C, and 15N backbone chemical shift assignments of the apo and the ADP-ribose bound forms of the macrodomain of SARS-CoV-2 non-structural protein 3b

Paper publication: Impressive first results obtained by Professor Lucia Banci, CERM Florence, and co-workers with a 1.2 GHz NMR spectrometer, which will provide a basis for NMR investigations targeted at obtaining small-molecule inhibitors interfering with the catalytic activity of Nsp3b.

Cantini, F., Banci, L., Altincekic, N. et al.: 1H, 13C, and 15 backbone chemical shift assignments of the apo and the ADP-ribose bound forms of the macrodomain of SARS-CoV-2 non-structural protein 3b. Biomol NMR Assign 14, 339–346 (2020). Read more

Topic 4 enews september 9 2020

Solid State NMR Spectroscopy in Pharmaceutical Sciences from Drug Delivery to Formulation Development

On-demand webinar: Dr. Yongchao Su, Merck & Co., presents the roles of ssNMR in pharmaceutical development, providing the structural basis for the design of drug substances and products. Advanced techniques including proton detection under ultrafast magic angle spinning and dynamic nuclear polarization for overcoming low sensitivity challenges of natural abundance crystalline compounds, amorphous drug substance and solid dosages are discussed.Read more