Application innovation — a hallmark of MALDI

From 1985 to the present, MALDI has evolved into a powerful, highly versatile technology. The range of its application is nothing short of astounding. MALDI coupled to time-of-flight mass spectrometry is used to sequence proteins, map biomolecules in tissues, identify microorganisms, and analyze several thousand biochemical assays in a day.

Insights from research featured in our celebration of MALDI are testament to the diverse advancements MALDI has and continues to catalyze in science.

"High Spatial Resolution Lipid Imaging" - Featured PosterNote

Phospholipid maps provide key insight into cell signaling pathways but stains are largely unable to distinguish species within a specific lipid family.  MALDI imaging combines the specificity of mass spectrometry to distinguish individual species with the ability to map abundance within the tissue architecture.  

Bruker’s rapifleX is ideally suited for mapping lipids in tissue with unsurpassed specificity and spatial resolution. In the latest PosterNote. rapifleX is used to map phospholipids in human lymphoma, revealing highly detailed molecular maps that are found to correlate with histological features of the tissue.

High Spatial Resolution Lipid Imaging
High Spatial Resolution Lipid Imaging