Micro Imaging

Micro imaging
Courtesy of M. Wenzler and B. Schneider
Max Planck Institut für chemische Ökologie, Jena, Germany

13C Inverse detected Saccharose Transport in Anigozanthos Plants

Detection of sugar transport in the Anigozanthos stem to determine the nectar production mechanisms. The plant was fed with 13C labelled glucose. 

The C1-a bound protons (coloured) overlayed to the proton image. The absorbed sugar can be found in the vascular bundles only and is not stored in the tissue. 400 MHz, 9.4 T, Cryo probe for micro-imaging.

Micro Imaging
Courtesy of C.Zweifel and C.Handschin ETH Zürich

Cooking of Spaghetti

Spaghetti were cooked outside of the magnet with four different cooking times and then mounted together with a uncooked one for comparison in the imaging probe.

Cooking times: (1) 0 min, (2) 1 min, (3) 3 min, (4) 5 min,  (5) 10 min

The cooking process of pasta is visualized by three easy distinguishable zones in cross section images through spaghetti, indicating volumes of uncooked, intermediate and finished cooking.

 

 

Micro Imaging
Movie: Courtesy of Peter Hummel

Dissolution of Tablets

The dissolution and the drug release of tablets is controlled by various properties: tablet material, morphological tablet structure, surface material, properties of the gel layer during dissolution, ph value of the environment during dissolution etc.

The dissolution process can be visualized by time resolved  2D and 3D images, observing the water protons.

The image artefact at the left side of the dark tablet shape is caused by a paramagnetic colour  from the letters of the trademark, written on the tablet surface.

The dissolving process starts at one position, where the outer cover of the tablet was dissolved first. After the start a faster dissolving process continues

Micro Imaging
Courtesy of U. Flögel, C. Jacoby,
J. Schrader, Heinrich-Heine-Universität Düsseldorf, Germany

Detection of Collagen-induced Arthritis by 19F MRI

Perfluorocarbon-loaded monocytes/macrophages enter sites of inflammation in a mouse.

400MHz, 9.4 T, 30 mm 1H/19F resonator

Overlay of the 19F image (colored) over the 1H image (grey).