Structural and Cell Biology - Nanoscale Mechanical Properties

Structural and Cell Biology

Quantitative Nanomechanical Characterization at the Cellular Level

The mechanical properties of cells and their surroundings are integral to the cellular performance of living organisms. Cellular mechanical properties play in important role in biological processes, such as cell differentiation, growth, ageing, movement, wound healing, metastasis, and drug delivery. Cellular biochemical and genetic response can be linked to the mechanical properties of cells and their surroundings. Measurements of these biophysical changes can be used to understand cell state and function.

Cellular Nanomechanics

Bruker has developed multiple technologies to measure the mechanical properties of individual cells and localized structures at the tissue level. Based on nanoindentation techniques, the effect of input mechanical signals on cellular behavior and the results of biochemical cues on cellular architecture changes can be quantitatively measured. Bruker’s mechanical phenotyping test equipment provides new ways to characterize the interdependencies of mechanical behavior and cellular state or function.

Application Notes

Standalone Test Equipment for Cell/Tissue Characterization

Hysitron TI 980 TriboIndenter | Bruker

TI 980 TriboIndenter

Bruker's most advanced nanomechanical and nanotribological test instrument, operating at the intersection of maximum performance, flexibility, reliability, sensitivity and speed.

Hysitron TI 950 TriboIndenter | Bruker

TI 950 TriboIndenter

Versatile nanomechanical and nanotribological test instrument, supporting a broad range of hybrid and correlative characterization techniques.

Hysitron TI Premier | Bruker

TI Premier

Dedicated nanomechanical test instruments, providing an essential toolkit for nanoscale mechanical characterization within a compact platform.

Microscope Instruments for Cell/Tissue Characterization

Hysitron TS 75 TriboScope | Bruker

TS 75 TriboScope

Quantitative, rigid-probe nanoindentation and nanotribological characterization on your existing AFM.

Hysitron BioSoft In-Situ Indenter | Bruker

BioSoft In-Situ Indenter

The first of its kind instrument for multiscale quantitative mechanical testing of biological materials and hydrogels.