DeutEx Software
Fast HDX Analysis
Versatility for structure & dynamics
DeutEx: Speed and precision for HDX-MS analysis
Complete HDX-MS Workflow Integration
DeutEx seamlessly integrates with Bruker’s LC-MS/MS solutions by offering an efficient interface for the processing of HDX data and automated calculation of deuteration levels across time points and replicates
- Retention time-based filtering and extraction of multiple charge states
- Compatible with protein modifications and fully compliant with Unimod syntax
- Interactive review and manual data curation
- Export options aligned with HDX-MS reporting standards
- Visualization tools for structural and dynamic protein analysis including statistics
Save Time, Gain Confidence in your HDX Experiments
DeutEx eliminates bottlenecks in HDX-MS data processing. Researchers benefit from:
- Faster turnaround for complex datasets
- Designed for multi-condition HDX experiments
- Reliable and reproducible results
- Compliance with HDX-MS best practices for publication
- Data visualization including statistics
- Ease of use
From Raw Data to Intuitive Insights: Automated HDX MS Visualization at Every Level
Fully automated visualization tools that transform HDX-MS results into clear, interpretable figures with integrated statistical filtering:
- Coverage maps
- Rainbow or differential heat maps
- Butterfly or Woods plots
- Direct integration with PyMol for 3D structure coloring
DeutEx supports your HDX workflows
DeutEx empowers research in:
- Drug Design & Development: Identify binding sites and optimize drug candidates
- Biopharmaceuticals: Ensure stability and efficacy of therapeutic antibodies
- Structural Biology: Complement X-ray, cryo-EM, and NMR studies
- Disease Research: Investigate protein mechanisms and therapeutic targets
"DeutEx has been a very intuitive software to use. The data processing workflow is easy to understand and any changes to the settings or data used for the calculations (e.g. adjusting isotopic distribution or retention time range) are reprocessed very quickly."
Liliana Pedro, Ph.D., Senior Scientist, Orion Pharma, Espoo, Finland
"We like it that besides the deuterium uptake plots, we can also visualize envelop widths and peptide log intensities across the different time points, making it easier to control for outliers and errors."
Kai Sinervo, Senior Research Scientist, Orion Pharma, Espoo, Finland
