Fourier 80
Highlights
Powerful benchtop NMR for teaching, research, and routine analysis
The Fourier 80 brings high‑quality NMR into everyday laboratory workflows by combining a stable cryogen‑free magnet, optimized probe technology, and practical automation. Its digital lock, efficient gradients, controlled temperature range, and optional sample changer make routine measurements fast, reliable, and easy to integrate into teaching, QC, and research environments. The result is a compact system that delivers consistent performance with minimal setup and training.
Fourier 80 Configurations
Workhorse for Routine Structure Verification:
1H/13C (H/C) system
The Workhorse configuration extends proton measurements with carbon capabilities, enabling routine structure verification. It is suited for chemists who regularly need more confirmation than a simple screening measurement, such as validating reaction outcomes or confirming compound identity. This makes it a dependable everyday tool for laboratories that balance speed with structural confidence.
If you are interested in Workhorse, read also about the Fourier 80 Duo.
TripleXpert for Advanced Analytical Flexibility:
1H/13C|19F (H/C|F) system
The TripleXpert configuration expands analytical capabilities with fluorine detection, making it ideal for chemists working with fluorinated compounds. It is well suited for more advanced structure verification, reaction monitoring, and impurity analysis where heteronuclei play a key role. TripleXpert supports confident decision‑making in research environments that require greater molecular insight beyond routine proton and carbon analysis.
Multi‑Talent for Maximum Versatility:
Multinuclei system
The Multi‑Talent configuration offers the highest flexibility by supporting multiple heteronuclei, enabling a broad range of applications across chemistry workflows. It is designed for chemists and researchers working with diverse compound classes and need the freedom to adapt to changing analytical requirements. The Multi‑Talent provides a versatile platform for comprehensive structure elucidation and advanced research applications.
High Performer for Fast Analytical Decisions:
1H‑only system, optimised specifically for 1H measurements
The High Performer is designed for users who primarily work with small molecules and need fast, reliable answers. It is ideal for analytical chemists who want a quick pass/fail result to decide whether to continue, modify, or stop an experiment.
Versatility, Flexibility and Precision
The Fourier 80 Benchtop NMR spectrometer advances discoveries by providing a compact, user-friendly, and sophisticated NMR solution. It enhances academic research and NMR education, transforms pharmaceutical development, streamlines industry processes, and advances the accurate detection of new psychoactive substances in forensic drug testing.
The Fourier 80's intuitive software solutions simplify high-quality data acquisition, allowing researchers to focus on their projects without extensive training. Its flexibility enables seamless workflow adaptation from the benchtop to dedicated NMR laboratories, boosting efficiency and productivity. With robust technical specifications, including various nuclei selection options and automation capabilities, the Fourier 80 offers cutting-edge technology without requiring extensive resources. This combination of ease of use, flexibility, and precision makes the Fourier 80 an indispensable tool for achieving significant advancements in life and material science.
Fourier 80 Technical Advantages
Magnet & Probes
- Cryogen free permanent magnet for stable, everyday use
- Available configurations: Workhorse, Multi-Talent, High Performer, and TripleXpert
- Optimized X channel sensitivity (19F, 31P, 29Si- for the Multi-Talent)
Automation
- PAL RSI sample changer supporting 108 samples (incl. 12 reference samples), with option to extent to 252 samples in total
- Enables fully unattended overnight/weekend sequences
- Controlled directly in GoScan or TopSpin
Digital Lock
- External lock - no deuterated solvent required
Adjustable Temperature (AT)
- 25–60 °C controlled in GoScan and TopSpin
- Compatible with automated workflows
- Elevate your sample temperature without compromising performance
Pulsed Field Gradient (PFG)
- Robust solvent/water suppression, DOSY, and 2D NMR with efficient, artifact free performance
- Gradient strength ≥ 0.25 T/m
Fourier 80 Benefits
- Compact footprint, designed for the routine laboratory use
- Easy maintenance and minimal cost of ownership
- Perform complex molecular analysis
- Provides higher sample throughput
- Optimized synthesis and process control directly on the bench
- Automated data interpretation
- Use Bruker high-field system workflows on the benchtop
- Suitable for comprehensive range of applications
- Reduces errors and maximizes efficiency
Fourier 80 Automation Suite
New Rack Configuration:
The new rack configuration keeps the same instrument footprint while increasing room temperature capacity and introducing individually standing tubes.
Standard configuration:
- 1 × 12-position reference rack
- 2 × 48 room temperature positions
Total: 108 positions
Upgrade option:
- Upgrade with another tray holder with 3 × 48 positions
- Total upgrade capacity: 252 positions
What is new:
- All tubes are now standing individually
- Same footprint of the legs
- Additional cooling unit (optional and upgradeable at any later stage)
- Additional heater unit (optional and upgradeable at any later stage)
- Barcode reader (optional and upgradeable at any later stage)
The Fourier 80 Automation Suite enables automated sample handling for routine NMR workflows. It combines flexible sample capacity, temperature control, and reliable operation in one compact benchtop solution.
Videos
Fourier 80 – The Trusted NMR Spectrometer for Every Lab
The Fourier 80 benchtop NMR spectrometer is a versatile, compact, and cost-efficient instrument for different types of labs. It enhances academic research and NMR education, transforms pharmaceutical development, streamlines industry processes, and advances the accurate detection of new psychoactive substances in forensic drug testing. By providing high-quality NMR data, intuitive software, real-time monitoring, and automation possibilities, the Fourier 80 is a reliable asset for scientists, educators, pharmaceutical developers, and industry professionals.
Academic Researcher Labs:
From Push-Button Ease to Customization
The Fourier 80 benchtop NMR spectrometer is designed to empower academic researchers with its compact, cost-efficient, and user-friendly features, delivering high-quality NMR data for all researchers with or without prior NMR expertise. It offers full flexibility with customizable pulse sequences and advanced software integration. Ideal for structure verification and molecular analysis, Discover how the Fourier 80 can enhance your academic research.
Teaching Labs:
Hands-on NMR Education
The Fourier 80 benchtop NMR is enhancing educational curriculum in chemistry and physics. By integrating practical applications and using intuitive software that delivers fast results with a single click, students gain hands-on experience and a deeper understanding of NMR spectroscopy. Comprehensive software for in-depth learning minimizes the risk of instrument damage to instruments during student use. Equip the next generation of scientists with practical NMR skills through the Fourier 80.
Pharmaceutical Industry:
Enhanced Research and Quality Control
The Fourier 80 benchtop NMR spectrometer offers comprehensive structural analysis for routine synthesis control and quality assessment, ensuring rapid screening of reagents and raw materials to prevent costly synthesis failures. With full automation and minimal maintenance requirements, it integrates seamlessly into QC laboratories, enhancing productivity and ensuring compliance with GMP standards. Transform your pharmaceutical research and quality control with the Fourier 80.
Chemical Industry:
Production Efficency and Innovation
The Fourier 80 benchtop NMR spectrometer is compact, cost-efficient, and user-friendly, fitting on a regular laboratory bench without requiring special infrastructure. It provides high-quality data for structure verification, reaction monitoring, and process control, helping chemists optimize synthesis and ensure product quality. Its intuitive software facilitates data acquisition and interpretation, enhancing productivity and efficiency in chemical research and development. Discover how the Fourier 80 can support your chemical processes and innovations.
Drug Testing and Toxicology:
Redefining Forensic Drug Testing
The Fourier 80 benchtop NMR spectrometer is revolutionizing forensic drug testing by providing rapid and automated identification and quantification of new psychoactive substances (NPS) without the need for pre-qualified references. The Fourier 80's compact design and capacity to deliver conclusive results in minutes enhance the efficiency of forensic investigations, making it ideal for crime laboratories and border control authorities. Explore how the Fourier 80 can elevate your forensic drug testing.
Applications
The Fourier 80 is a versatile tool in NMR spectroscopy, designed to enhance a broad spectrum of applications. Whether it's verifying molecular structures, optimizing chemical processes, or conducting forensic analysis, the Fourier 80 delivers precise and reliable results. It supports academic research, quality control in industries, and hands-on training in educational institutions, making automation and high-field NMR system workflows accessible on your benchtop.
All Fourier 80 related Application Notes:
Specifications
The High Performer: 1H-only system with 1H sensitivity of ≥ 240:1 or ≥ 220:1 when pulsed field gradient (PFG) incl. (1% ethyl benzene)
The Workhorse: 1H/13C system with 1H sensitivity of ≥ 180:1 or ≥ 160:1 when PFG incl. (1% ethyl benzene)
TripleXpert: 1H/13C|19F system with sensitivity optimized for the X-channel,
PFG incl.; sensitivity:
1H: ≥ 110:1 (1% ethyl benzene)
19F: ≥ 110:1 (0.5% TFT in CDCl3)
The Multi-Talent: 1H/X system with X being any of the 15 software-selectable X-nuclei (²H, ⁷Li, ¹¹B, ¹³C, ¹⁵N, ¹⁹F, ²³Na, ²⁷Al, ²⁹Si, ³¹P, ⁵¹V, ⁷⁷Se, ⁷⁹Br, ¹¹⁹Sn, ¹²⁹Xe), and sensitivity optimized for X-channel, PFG incl.; sensitivity:
1H ≥ 100:1 (1% ethyl benzene)
19F ≥ 90:1 (0.5% TFT in CDCl3 )
31P ≥ 130:1 (0.485M TPP in Acetone-d6)
29Si ≥ 25:1 (100% HMDSO)
- 1H Resolution (@ 50/0.55/ 0.11% signal height) :
- Standard: ≤ 0.4/ 15/ 30 Hz
- HD-Option: ≤ 0.3/ 10/ 15 Hz - Gradient Strength ≥ 0.25 T/m (25 G/cm)
- Adjustable temperature of 25°C - 60°C*
- Digital Lock: External, no deuterated solvents needed
- Automation: PAL RSI sample changer; up to 120 samples + 12 reference samples
- Sample Tubes:
- Standard 5mm O.D., 7’’-long NMR tubes
- Flame sealed tubes possible
- J-Young tubes possible, but only in manual mode (not compatible with sample changer) - Dimensions:~50 cm x 70 cm x 60 cm (Height x Width x Depth)
- Weight: ~94 kg
- no liquid nitrogen or helium required
- no water cooling required
- power consumption typically <300 W
- power: 100 – 240 V, 50 – 60 Hz
- no additional venting required
- Lab Temperature: 18-28°C; Measurements at sample temperature > 40°C: 18-25°C
- Adjustable sample temperature needs compressed air or nitrogen at 5 bar max
- When using the adjustable temperature, the incoming supply gas temperature needs to be min. 5°C lower than the target temperature
Accessories
HPLC pump (RxnLab accessory optionally available)
Thermostat bath (RxnLab accessory optionally available)
Testimonials
Dr. Jean-Francois Ayme,
University of Liverpool, UK“The Fourier 80 benchtop NMR is an invaluable tool for Quality Control, offering versatility unmatched by other analytical instruments. It is reasonably priced and requires no maintenance, making it a cost-effective choice. The system delivers 90% of the answers you need efficiently, reducing the reliance on high-field NMR systems for routine analysis. The excellent cost/benefit balance ensures a quick return on investment, while the high-quality data it provides is impressive.
Unlike sending samples to an NMR service company, using the benchtop NMR allows you to gain deeper insights into your samples and the capabilities of NMR technology. Although it operates at a low field strength, the hands-on experience with the benchtop spectrometer enhances your understanding and optimizes problem-solving.”
Dr. Filip Szczypinski,
Durham University, UK“The Fourier 80 with the autosampler is the most efficient NMR system I have ever worked with. It enables real-time research and new discoveries with high throughput, without compromising the NMR facilities. The seamless integration of Python APIs in TopSpin opens up a world of customized end-to-end solutions for individual needs and problem statements. The recent solvent suppression implementation is a game changer.
The application support is outstanding, providing excellent knowledge transfer on what works with high-field NMR and how it can be adapted to benchtop systems.”
Cassie Yang,
Principal Research Scientist at Abbvie“The Fourier 80 has facilitated the implementation of workflows for controlling the quality of our incoming materials. It offers a simpler and cost-efficient alternative to high-field NMR systems. Combined with the intuitive interface of MDrive, our non-expert users can directly submit their samples and retrieve their data with ease, while ensuring data integrity. As analysts, our role now only involves validating the final results.
With no maintenance requirements, utilizing the Fourier 80 for our quality control applications has thus allowed us to both save time on high-field instruments and reduce the workload of our analytical team. This way, as experts, we can focus on addressing more demanding analytical challenges, while our users independently perform their QC analysis on raw materials.”
Thomas Rudszuck,
PhD Student in the group of Prof. Gisela Guthausen,
Karlsruhe Institute of Technology, Karlsruhe, Germany“The operation of the device is very intuitive and requires only minor manual parameter adjustments to carry out standard experiments. This results in great potential for many new applications of NMR spectroscopy. In addition, there is the possibility of teaching students the content of the lectures directly with relatively little effort using spectroscopy experiments. Especially for the lecture “NMR in Engineering”, where the focus is often on industrial applications, a robust and easy to use device is very impressive for students.”
Dr. Stuart J. Elliott,
Postdoctoral Research Fellow in the group of Prof. Sami Jannin,
Université Claude Bernard Lyon 1, Lyon, France“Amongst others, I am responsible for teaching NMR spectroscopy to our next generation of scientists. Since the Fourier 80 can be operated with very little training and minimal preparation, it is an excellent tool for introducing NMR spectroscopy to our students. It is very advantageous to be able to start experiments quickly, in contrast to high field NMR systems, where there is sometimes a prolonged interaction with the hardware before commencing experiments. With the Fourier 80, the only contact you have with the instrument is the insertion of the sample.
For my own research, the Bruker benchtop system has been incredibly beneficial. I can’t wait to develop new methodologies, e.g. related to singlet-NMR, and the introduction of pulsed field gradients opens doors to so many other avenues of research.”
Dr. René Jakelski,
Daikin Chemical Europe GmbH, Düsseldorf, Germany“As one of the lucky beta-testers, Daikin was able to use the Fourier 80 to determine structures and impurities, for the QA of incoming material and novel synthesized components. Due to the self-explanatory user interface and the quick sample preparation even inexperienced users could be trained quickly and reliably. Coming from high-field NMR, we used the Fourier 80 for routine measurements, without the need for additional lab space, and could free precious measurement times.”
Prof. Sami Jannin,
Université Claude Bernard Lyon 1, Lyon, France“The Fourier 80 is a compact, easy to use FT-NMR benchtop instrument that has good sensitivity and resolution even at 80 MHz. When compared to high field NMR it also has some advantages such as resilience of the lock, shim and nutation angle with respect to sample formulation, as well as longer 13C hyperpolarization lifetimes. With very little training needed, the Fourier 80 is perfect for teaching students, performing research with hyperpolarized 13C and 1H spins, and even for routine NMR. Whenever low field NMR could be used to fulfil specific needs, I would certainly recommend the Fourier 80.”
Prof. Andre Simpson,
University of Toronto, Ontario, Canada.“We love the Fourier 80 MHz, it has been working 24/7 since it arrived. What sets it apart is its flexibility to run all experiments from our high field systems, including all the pulse programs we have written ourselves. Not only does this make it easier to integrate into the lab, but it also revolutionizes what we can do at low field and truly establishes it as a powerful research tool. The Fourier 80 MHz has far exceeded our expectations and has become a workhorse impacting research across all our scientific programs.”
Constance Braouet,
Master Student, Hochschule Fresenius, Idstein, Germany“As a student you do not often have the possibility to work on an NMR spectrometer. That’s why I felt honored to be able to work with the Fourier 80 during my Master thesis and to explore the capabilities of this new instrument. The Fourier 80 has a lot of potential in the analysis of small organic molecules (< 500 Da) and few-component mixtures and can even be applied for quantification purposes. It is a method, which students can easily use in their laboratorial education, even if they have not heard a lot on NMR priorly.
I am excited to test further features of the Fourier 80 and to see how students cope with the instrument, which they will be using for the analysis of organic synthesis products.”
Shop for Fourier 80 Consumables at Bruker Store
Bruker offers a range of certified consumables for the Fourier 80 benchtop instrument. Explore our selection of Fourier 80 consumables, specifically designed to ensure optimal performance and reliability in your experiments.
Downloads
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Chemical Clues from Every Shift
(PDF, 3 MB)
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Fourier Benchtop Brochure
(PDF, 3 MB)
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Fourier 80 - Mimic a GHz - Flyer
(PDF, 471 KB)
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The Fourier 80 PAL RCI
(PDF, 466 KB)
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Automatic Signal Region Detection in 1H NMR Spectra
(PDF, 1 MB)
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Deep learning-based phase and baseline correction
(PDF, 3 MB)
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Enhanced Process Control - Flyer
(PDF, 1 MB)
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GoScan with Identity Management (UM)
(PDF, 1 MB)
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Fourier 80 Multi-Talent Versatile. Innovative. Robust.
(PDF, 922 KB)
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The Fourier 80 Benchtop NMR for Chemical Analysis
(PDF, 614 KB)
