Benchtop NMR | System | Solutions

Najważniejsze informacje

Highlights

Cryogen-free

The Fourier 80 can be installed in the fume hood or on the bench without the need for new infrastructure, providing easy maintenance and minimal cost of ownership.

80 MHz

The Fourier has been designed for the highest data quality and stability at 80 MHz, with excellent lineshape, resolution and sensitivity.

Flexibility

Adjustable temperature for the Fourier 80 allows samples to be measured from 25°C up to 60°C

Precision

Bring NMR directly to the reactor with patented temp-controlled transfer lines and a flow rate of up to 10 bar for analyzing chemical reactions in real-time

Now Available: Adjustable Temperature for the Fourier 80

Cechy charakterystyczne

Features

Easy to Install: The Fourier, an 80 MHz high-performance nuclear magnetic resonance (NMR) benchtop spectrometer designed for the routine laboratory. With a cryogen-free magnet design, the Fourier makes NMR accessible in the lab where users and operators work. It can be installed in the fume hood or on the bench without the need for new infrastructure, providing easy maintenance and minimal cost of ownership. The performance of the benchtop, combined with the intuitive software, means any lab can now incorporate the definitive analytical answers only NMR can provide.

Easy to Use: The Fourier features GoScan™, a newly developed modern interface which guides users through pre-defined, dedicated workflows. Novice NMR users can use pre-defined data acquisition choices in the GoScan software, or customize them, while experienced users can use Bruker's industry standard TopSpin™ software for more detailed acquisition parameters.

Easy to do More: The different features of the Fourier 80 were designed to offer a compact and advanced analytical system that requires no special infrastructure, lengthy installation, or complex training, bringing NMR technology to the wider laboratory market. Pulsed field gradients, an automatic sample changer, and adjustable temperature all provide higher sample throughput, optimized synthesis, and process control. The Fourier RxnLab now allows researchers the ability to bring NMR directly to the reactor for real-time chemical analysis while the GxP Readiness Kit enables NMR functionality in both development and manufacturing labs to be scaled seamlessly from benchtop to enterprise operations.

Korzyści

Benefits

Easy to own and maintain

Cryogen-free permanent magnet
No new infrastructure required
Compact footprint
Installs on bench or in fume hood
Minimal cost of ownership

Aplikacje

Applications

Benchtop NMR spectroscopy quantifies hand sanitizer ethanol content in seconds

Hand hygiene has been at the center of the global response to the COVID-19 pandemic, with alcohol-based sanitizers playing a key role. However, several reports indicate that hand sanitizer fraud is prevalent. Rapid testing methods such as benchtop Nuclear Magnetic Resonance (NMR) spectroscopy can determine the alcohol content or percentage volume (% vol) of hand sanitizers in seconds, preventing fraud

Application Note

Specyfikacje

Specifications

Operating Frequency:	80 MHz (1H)
Nuclei:	1H-only, 1H/13C, 1H/31P or 1H/129Xe (contact us for more)
1H Sensitivity:	Measured on 1% Ethyl Benzene: 1H-only systems: ≥ 240:1 or ≥ 220:1 when pulsed field gradient incl. 1H/X systems: ≥ 160:1 (incl. pulsed field gradient)
Gradient strength:	≥ 0.25 T/m (25 G/cm)
Adjustable temperature:	25°C - 60°C*
Automation:	PAL RSI sample changer; up to 120 samples + 12 reference samples
1H Resolution: (@ 50/0.55/ 0.11% signal height)	Standard: ≤ 0.4/ 15/ 30 Hz < 16 Hz @ 0.55% peak height HD option: ≤ 0.3/ 10/ 15 Hz
Digital Lock:	External, no deuterated solvents needed
Sample Tubes:	standard 5mm diameter, 7’’-long NMR tubes: compatible with Young tubes
Dimensions:	~50 cm x 70 cm x 60 cm (Height x Width x Depth)
Weight:	~94 kg
Lab Temperature:	18-28°C; Measurements at sample temperature > 40°C: 18-25°C
Lab Infrastructure needed:	no liquid nitrogen or helium required no water cooling required power consumption typically <300 W power: 100 – 240 V, 50 – 60 Hz no additional venting required AT needs compressed air or nitrogen at 5 bar max.
	*Incoming supply gas temperature must be min.5°C lower than the target temperature

Akcesoria

Fourier 80 with PAL RSI

Tackle the challenges. Remove the barriers.

For basic research, the Fourier offers unprecedented flexibility. It can be operated with the same TopSpin™ software that runs Bruker’s high-field NMR instruments, so scientists have the freedom to adjust their workflows and techniques from the benchtop to the dedicated NMR lab, and back.

Fourier CrimeLab

Get unequivocal forensic evidence about unknown substances

Fourier ChemLab

Convenient, straightforward access to NMR structure verification

Fourier EduLab

Give students hands-on experience with the power of NMR

RxnLab

The Fourier 80 also features the advanced reaction monitoring capabilities of Fourier RxnLab™, which offers InsightMR™ patented insulated reaction paths and control software to minimize temperature loss, optimize process control, and monitor reaction outcomes. Czytaj więcej

Webinary

Features and applications with NMR Fourier 80 and EPR Magnettech ESR5000 benchtop systems.

Thursday, August 12, 2021

NUS, NOAH, No Idea? Advanced Experiments with Fourier 80

Barbara Czarniecki, Applications Scientist at Bruker will explain how the Fourier 80 can be used to perform advanced NMR experiments.

April 20, 2022

New Psychoactive Substances (NPS): automated identification and quantification

Keeping pace with illicit drugs known as New Psychoactive Substances (NPS), also referred to as ‘legal highs,’ presents a huge challenge to border control authorities and police forces across the globe.

Referencje

Testimonials

Constance Braouet, Master Student, Hochschule Fresenius, Idstein, Germany.

“As a student you do not often have the possibility to work on a NMR spectrometer. That’s why I felt honored to be able to work with the Fourier 80 during my Master thesis and to explore the capabilities of this new instrument. The Fourier 80 has a lot of potential in the analysis of small organic molecules (< 500 Da) and few-compound mixtures and can even be applied for quantification purposes. It is a method, which students can easily use in their laboratorial education, even if they have not heard a lot on NMR priorly. I am excited to test further features of the Fourier 80 and to see how students cope with the instrument, which they will be using for the analysis of organic synthesis products.”

Thomas Rudszuck, PhD Student in the group of Prof. Gisela Guthausen, Karlsruhe Institute of Technology, Karlsruhe, Germany.

“The operation of the device is very intuitive and requires only minor manual parameter adjustments to carry out standard experiments. This results in great potential for many new applications of NMR spectroscopy. In addition, there is the possibility of teaching students the content of the lectures directly with relatively little effort using spectroscopy experiments. Especially for the lecture “NMR in Engineering”, where the focus is often on industrial applications, a robust and easy to use device is very impressive for students.”

Prof. Sami Jannin, Université Claude Bernard Lyon 1, Lyon, France.

“The Fourier 80 is a compact, easy to use FT-NMR benchtop instrument that has good sensitivity and resolution even at 80 MHz. When compared to high field NMR it also has some advantages such as resilience of the lock, shim and nutation angle with respect to sample formulation, as well as longer ¹³C hyperpolarization lifetimes. With very little training needed, the Fourier 80 is perfect for teaching students, performing research with hyperpolarized ¹³C and ¹H spins, and even for routine NMR. Whenever low field NMR could be used to fulfil specific needs, I would certainly recommend the Fourier 80.”

Dr. Stuart J. Elliott, Postdoctoral Research Fellow in the group of Prof. Sami Jannin, Université Claude Bernard Lyon 1, Lyon, France.

“Amongst others, I am responsible for teaching NMR spectroscopy to our next generation of scientists. Since the Fourier 80 can be operated with very little training and minimal preparation, it is an excellent tool for introducing NMR spectroscopy to our students. It is very advantageous to be able to start experiments quickly, in contrast to high field NMR systems, where there is sometimes a prolonged interaction with the hardware before commencing experiments. With the Fourier 80, the only contact you have with the instrumentation is the insertion of the sample. For my own research, the Bruker benchtop system has been incredibly beneficial. I can’t wait to develop new methodologies, e.g. related to singlet-NMR, and the introduction of pulsed field gradients opens doors to so many other avenues of research.”

Prof. Andre Simpson, University of Toronto, Toronto, Canada.

“We have been waiting specifically for a Bruker benchtop system. We run the Environmental NMR Center in Canada and see low field NMR as the next critical step forward that will bring in new users and make NMR more accessible to the masses. But developing environmental applications is very challenging, and arguably even harder at low field. Therefore, we need the most state-of-the-art tools available. Furthermore, Bruker’s Fourier 80 runs Topspin and implements pulse programs in an identical manner to their high field systems. Over the last 2 decades, we have developed hundreds of custom pulse programs at high field, these can be transferred to the Fourier 80 without worrying about “if it will work” or “can your system do XYZ” as would be the case with a 3^rd party system. In combination with pulsed field gradients the Fourier 80 expands the application of advanced experiments, essential for working with complex samples.”

Dr. René Jakelski, Daikin Chemical Europe GmbH, Düsseldorf, Germany.

"As one of the lucky beta-testers, Daikin was able to use the Fourier 80 to determine structures and impurities, for the QA of incoming material and novel synthesized components. Due to the self-explanatory user interface and the quick sample preparation even inexperienced users could be trained quickly and reliably. Coming from high-field NMR, we used the Fourier 80 for routine measurements, without the need for additional lab-space, and could free precious measurement times."