Target analysis screening quantitation

TASQ® Software

TASQ® provides a turnkey data analysis solution for when there is a requirement to screen, confirm and/or quantify hundreds of compounds in a single analysis

Screen to Quant

Simple to use

tasq

Punti salienti

Target analysis screening quantitation

Rapid in-depth data analysis and mining

Extended Quantification Workflows
In addition to standard multipoint calibration, semi-quantitative calibration workflows are supported and can be combined in one analysis.
Generates Insights
Exploit large, complex high-resolution accurate mass and also ion mobility resloved data sets. All qualitative and quantitative analysis is supported in ‘compound-’ or ‘sample-’centric views to ensure the most relevant information is extracted.
Simple and intuitive
Easy to learn and master for users in routine testing laboratories. Fast, easy method setup with menu driven, quick start wizard to expertly guide users through qualitative and quantitative workflows.
Rapid and flexible
No matter how complex a sample may be, TASQ will Screen, Confirm, Quantify or Semi-Quantify. Preconfigured reports or export to LIMS for further customized processing and reporting.

Caratteristiche

TASQ

TASQ® addresses all customer needs in target screening and quantitation applications

TASQ® provides a turnkey data acquisition and analysis solution for screening, confirming and/or quantifying hundreds of compounds in a single analysis. Various quantification approaches are supported as batch workflows or for interactive evaluation:

  • Multi-point calibration
  • Legacy calibration analyses current samples against old calibration curves
  • Single-point calibration, ideal for rapid pass/fail threshold analysis
  • Standard addition procedure
  • Surrogate calibration
TASQ® covers a full automation workflow from setting up and starting the acquisition of sample batches, the processing of the acquired data and the result generation for hundreds of target compounds including report generation and LIMS export.

TASQ® enables quantification and screening of Triple Quadrupole (TQ), QTOF and timsTOF mass spectrometry data with uniform user and automation workflows.

The newest feature of TASQ® is the support for screening and quantification of compounds exploiting ion mobility on the Bruker timsTOF instrument line. Ion mobility can separate target compounds from complex matrix signals and the highly reproducible collisional cross section (CCS) acts as further identification criterion along with accurate mass, isotopic pattern, qualifier ions and retention



Examples of TASQ® Screening and quantitation reports


time to provide the highest confidence in compound identification and quantification.

TASQ® features a client-server architecture with integrated user management as well as batch, analysis and method handling. Remote access to the generated results is possible within the lab network for multiple users at the same time.

Benefici

TASQ

Supports data integration across multiple instruments

TASQ® supports data from various instrument lines including Triple Quadrupole, QTOF and timsTOF mass spectrometers. Screening and quantification can be applied for various types of chromatography instruments.

TASQ® minimizes false positive and false negative results by exploiting the unique features of Bruker instruments for accurate analysis

  • High resolution, accurate mass
  • Stable retention times
  • True Isotopic Pattern
  • Accurate, reproducible and rapid qualifier ion generation
  • The visualization of the unique MRSQC scoring speeds up overall data inspection and reduces review time
  • Provides greater confidence and more samples per unit time

Highly resolved and reproducible Ion Mobility values
TASQ® now supports accurate screening and quantification of compounds exploiting ion mobility on the Bruker timsTOF instrument. Ion mobility can separate target compounds from complex matrix signals and the highly reproducible collisional cross section (CCS) acts as a further identification criterion along with accurate mass, isotopic pattern, qualifier ions and retention time. This additional identification step increases confidence in results.
 

Applicazioni

TASQ

The versatility of TASQ® software supports a range of operations in applied markets

Although there are commonalities in the analysis of food, environmental and toxicology samples, the matrices can differ substantially between different samples.

In all cases, the analysis is complex and must follow strict regulations. The preset review parameters of TASQ® enable the software to handle the complexities of different systems with full regulatory compliance, in an easy-to-use package with clear reporting of results.

Supporting quality in the food industry
The versatility of TASQ® supports a wide range of applications in the food industry, where the product under analysis could range from a clear beverage, to a wheat sample. TASQ®, often as part of the Bruker TargetScreener solution, supports strict quality controls to determine food safety, quality, residual chemical content, such as pesticides, and region of origin.

Meeting environmental regulations
In the environmental sector different substances ranging from drinking water and wastewater to contaminated soil require testing.

The versatility of TASQ® can be used in multiple MS platforms, enabling dioxin analysis through an integrated solution that uses Triple Quad, QTOF and timsTOF technology. The TASQ® software facilitates data acquisition and analysis, and makes it easy to switch between plaforms for optimal results.

Delivering forensic and toxicology solutions
In the field of toxicology and forensics, the matrix is challenging and can range from any kind of body fluid or a pharmaceutical tablet. Applications range from toxicology quantification in a clinical enviroment or a post-mortem forensic analysis in a laboratory.

Supported by the reference database, the TASQ® software provides a failsafe screening tool. The software can also be linked to Bruker‘s MetaboScape® to identify an unknown workflow.


TASQ® automatically applies diagnostic ion criteria to hrXIC‘s to identify positive, negative and tentative detections.



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