We at Bruker JPK BioAFM are delighted to invite you to join us and a distinguished panel of experts for an international mini-symposium on Nanoscale Mechanobiology.
There is growing recognition that the study of the mechanical properties of cells, their 3D surrounding, and multicellular tissues is critical to understanding how cells regulate their molecular structure and self-organize. Cells actively sense and process the mechanical information provided by their extracellular environment. The study of cell mechanics is, therefore, key to understanding many complex biological mechanisms and their involvement in developmental and pathological processes. Nerve cells are also influenced by mechanical forces. Tissue stiffness, for example, plays an important role in how nerves function and develop, and possibly change after injury and differentiation.
Our panel of experts will share their knowledge and provide insights into their work and research in this exciting interdisciplinary field of science. They will focus on new and versatile Atomic Force Microscopy (AFM) methods for measuring the mechanical properties of biological samples in physiologically relevant conditions. They will present their findings on how AFM can be used to study and manipulate tissue mechanics and investigate the physical interactions between cells and their environment, and questions like why rigid tumors contain soft cancer cells will be answered.
Learn how Nanoscale Mechanobiology can provide new insights into your life science research.
5:00 pm Welcome address Carmen Pettersson, Senior Manager Product Marketing, JPK BioAFM, Bruker Nano GmbH
5:10 pm Using AFM for in vivo tissue mechanics measurements and manipulation Dr. Kristian Franze, University of Cambridge, UK
5:40 pm Mechanical regulation of cells and multicellular tissues Dr. Alexander Cartagena-Rivera, National Institutes of Health, Bethesda, MD, U.S.
6:10 pm Why do rigid tumors contain soft cancer cells Prof. Dr. Josef A. Käs, University of Leipzig, Germany
6:40 pm Open forum discussion Heiko Haschke
6:55 pm Closing Carmen Pettersson
Kristian Franze, Ph.D.
Reader in Neuronal Mechanics & Fellow of St. John's College, Department of Physiology, Development and Neuroscience, University of Cambridge, UK
Dr. Alexander Cartagena-Rivera
Section on Mechanobiology, National Institute of Biomedical Imaging and Bioengineering
Prof. Dr. Josef A. Käs
Principal Investigator & Head of the Soft Matter Physics Division, University of Leipzig, Germany