On-Demand Session: Causal Coupling Between Neural Activity, Metabolism, and Behavior Across the Drosophila Brain

       _{PRESENTATION HIGHLIGHTS:}

• [00:01:08] Introduction to the neural activity/metabolism relationship

• [00:03:04] Experimental methods for optical investigation of this relationship

• [00:05:54] Using whole-brain imaging methods to investigate functional neural and metabolic networks

• [00:11:33] Comparing signals within each brain region to determine the correspondence between neural activity and metabolic flux

• [00:15:24] Testing the necessity of neural activity for metabolic network structure and sufficiency for neural activity to drive metabolic flux

• [00:20:03] Using motor behavior to measure the coordination of neural and metabolic activity during action

• [00:24:02] Other applications

• [00:25:17] Implications for fMRI research

       _{PRESENTATION HIGHLIGHTS:}

• [00:00:23] Is there anything that you would like to discuss concerning the sensor you are using, given that the results may be influenced by the specifics of those proteins?
• [00:02:36] What about your choice of proteins in the optogenetics experiments, specifically?
• [00:04:02] How does a cell know how much ATP it will need for a specific process or activity?
• [00:07:06] Are these sensors only in neurons?
• [00:10:12] Are you going to try Lactate?

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