Accurate, reliable and state-of-the-art crystallography instrumention is key for accelerating research and making new discoveries.
Bruker’s single crystal X-ray diffractometers are used in laboratories worldwide to support both routine analysis and advanced studies. The experiences shared here demonstrate how Bruker's SC-XRD customers benefit from our advanced technologies, streamlined workflows, consistent performance and excellent customer service.
Continue reading to find out how Bruker's crystallography solutions enable efficient and high-quality structure determination all over the world.
High Data Quality and Fast Data Collection
"A big thank-you to Bruker for the excellent training and the support they provide us with. In total, these enhanced capabilities of the system (D8 QUEST GX) have opened up exciting new opportunities for time-resolved studies, fast phase transitions, and pioneering work in quantum crystallography.
The high data quality and fast data collection attract a lot of users - our crystallography group is having busy times now."
Dr. Fengxia Wei, Dr. Mohan Bhadbhade, Dr. Ruoming Tian - The University of New South Wales - Australia
D8 VENTURE: An Easy-to-Use System in a Cutting-Edge Environement
"As of day one, we achieved high-quality data sets from our organometallic samples using the D8 VENTURE.
Changing the wavelength only takes a few minutes. We can measure our highly absorbing Bi- or Pb-complexes using Mo-radiation and in the next minute run a pure organic sample with Cu-radiation. We routinely determine the absolute configuration of these structures."
Prof. Ganesan Prabusankar (left) - IIT (Indian Institute of Technology) - India
APEX4 for Snychrotrons
"Within our research we often introduce complex molecular rearrangements into the samples exposing our crystals to external disturbances, such as gases or temperature changes. For the data processing, structure solution, refinement, and investigation we found the APEX4 software suite extremely helpful.
APEX4 offers great engines to follow these changes on the structural level and, particularly, the visualization tools help us to better understand the processes involved. APEX4 can cope very well with the various frame formats we receive from the beam line. The package is very intuitive and therefore easy to learn, being a significant push for our capabilities to process challenging single crystal data."
Dr. Jose. S Costa - IMDEA Nanociencia - Spain
D8 VENTURE with METALJET - Exceeding Expectations
“We work at understanding the mechanisms underpinning basic biological processes of the cell at the atomic level. We decided to become the first installation of the D8 VENTURE METALJET single crystal diffraction system in Europe. Today, the performance of the METALJET system impresses us daily and the system is exceeding our expectations. Besides featuring the very bright source, the D8 VENTURE hardware and PROTEUM2 software are straight forward to use.
The D8 VENTURE has become a more important asset than anticipated. Being able to screen and collect data in-house helps us to make key decisions much faster and elaborate strategies for our ongoing structure determination projects.”
Dr. Jérôme Basquin - Max-Planck-Institute for Biochemistry, Germany
Exceptional Productivity - A Fast and Efficient In-House Solution
“Since we’ve acquired our Bruker system we have come on leaps and bounds in terms of the speed of data acquisition and ease of use of the machine and the software. It used to take us over 3 days to collect a single dataset on one of our older systems and now we can do the same data collection in just under 3 hours. The quality of the data coming off the machine is remarkably high, easily beating anything we had collected ever before on an in-house X-ray source. This gave us the possibility to accurately measure the very small Sulphur anomalous signal for our SAD experiments.
We call it our in-house synchrotron because the data that we can acquire on it can be on par with the synchrotron data.”
Dr. Dima Chirgadze - University of Cambridge, UK
D8 VENTURE - Accelerating Research
“My dream is that porous materials can change the world. The crystals we’re investigating are highly porous, very small and highly unstable, so if you try to measure their structures on a traditional diffractometer they just change during the measurement.
Thanks to the D8 VENTURE, we’ve now repeatedly determined COF structures from such challenging crystals which was something we needed the synchrotron to do before. It takes less than an hour even for an extremely small crystal. Now, all my students can do experiments to study the material properties and relationships by themselves. It’s very, very important, both for the students and the research environment, to provide access to these advanced and specialized instruments. Producing good scientists is more important for us than producing good papers.”
Na Yu - ShanghaiTech University - China
D8 VENTURE with METALJET - The best X-ray home source available to date
“The pressure to solve structures quickly is rapidly increasing – here, the new X-ray home source is a huge step forward to speed up this process because we can characterize crystals before synchrotron data collection. Thus, our measuring time there can be used much more efficiently or may, if one is really lucky, make the visit to the synchrotron beamlines even dispensable.”
“The Bruker METALJET X-ray source generates X-rays overcoming the brightness limitations of conventional rotating anodes. It is basically comparable to second generation synchrotron sources!”
Exerpt from an interview with Ashwin Chari, Trevor Huyton, and Ulrich Steuerwald, about a new D8 VENTURE METALJET at the Max-Planck Institute for Biophysical Chemistry.
If you would like to learn more about how our single-crystal X-ray diffractometer technology can enhance your research contact a Bruker expert or explore our range of solutions below.