Organic Chemistry

How many times have you see in papers on synthetic organic chemistry a section that looks like this: 
¹H NMR (CDCl3, 600 MHz): δH 6.71 (1H, d, J = 10.0 Hz, H3), 6.26 (1H, d, J = 10.0 Hz, H2), 4.81 (1H, dd, J = 1.4, 11.4 Hz, H10), 2.46-2.41 (1H, m, H11), 2.14 (3H, d, J = 1.5 Hz, H15)…and the supporting info contains page after page of NMR spectra?

NMR spectroscopy is a mainstay of analysis in organic chemistry. Whether NMR is used to elucidate novel structures, confirm the success of a reaction or monitor reactions directly, organic chemistry without NMR is almost inconceivable.
Bruker offers solutions for a wide variety of applications of NMR in organic chemistry. The Fourier 80 benchtop NMR can be used in or near the synthetic laboratory for quick checking of reaction steps or monitoring of the progress of a reaction. Easy-to-use high field NMR instruments offer the full range of NMR experiments with software that automates such tasks as structure elucidation and verification, purity analysis or yield determination. 

Specialized equipment can provide answers for complex problems. Cryogenically cooled probes can provide unprecedented sensitivity for carbon-13 NMR allowing for the study of materials that are not always amenable to experiments such as HSQC or HMBC. For many organic chemists the 1D carbon spectrum is still the gold standard for verification or identification of a molecule. 

NMR can be used to get real time insights into chemical reactions with accessories such as the InsightMR or InsightXpress.  These allow the continuous flow of a reaction solution through an NMR monitoring cell or the repeated rapid injection of reactants into an NMR tube in the magnet. 
Structure elucidation and verification can be computer assisted with tools such as CMCse or CMC-assist, or with the suite of MNova products. 

Relevant Products

Ascend 400

NMR Instruments

NMR to nieniszcząca technika analityczna generująca duży zbiór informacji. Dzięki niej można uzyskać szczegółowe informacje na temat struktury cząsteczkowej i procesów dynamicznych, a także bezpośrednio obserwować reakcje chemiczne.

Urządzenia EPR

Bruker's high-performance portfolio of EPR instruments offers a non-destructive analytical technique for the direct detection of paramagnetic species. Free radicals and transition metal ions can be identified and quantified in solids, liquids, gases, cells, and in vivo. Structural insights from the chemical structure to intermolecular interactions are obtained from both CW and Pulse EPR techniques.


The AvanceCore solution offers premium high-resolution NMR at a more affordable price, making NMR more accessible than ever before.
Avance Neo Console


The AVANCE NEO consoles for NMR feature even faster control, improved dynamic range and greater flexibility and scalability than ever before.
Avance Neo 400

Ascend NMR Magnets

Our Ascend line of magnets combines several of Bruker’s proprietary, innovative magnet technologies for best performance and cost efficiency.
Fourier 80

Fourier 80

Building on decades of experience creating top-quality NMR instruments, Bruker has reimagined high-performance NMR spectroscopy in a compact, cost-efficient form


Bruker can deliver top-performance probes for almost any application from routine 1H NMR measurements on small molecules to advanced research applications, including inverse experiments.
TBO Probe

TBO Probes

Triple Resonance Broad Band Probe (TBO)
magnettech ESR5000

Magnettech ESR5000

The Magnettech ESR5000 is an innovative research instrument with high quality performance. It offers dedicated and tailored turn-key solutions for specific quality control, medical, and pharmaceutical R&D applications.


The microESR is a small, portable research grade instrument and is also an ideal teaching tool for undergraduate chemistry labs. The spectrometer has a mass of only 10 kg and can easily fit in a fume hood or glove box, or be transported into the field. Plus, it requires no special installation or regular maintenance.


Designed to monitor reactions, enhance reaction understanding, gain confidence when transferring processes from lab to plant.

Recent Publications

Parallel NMR Supersequences: Ten Spectra in a Single Measurement

Ēriks Kupče*, Jonathan R. J. Yong,  Göran Widmalm and Tim D. W. Claridge