Modern Pharmaceutical Quality Control

Built-in Confidence, Proven Simplicity

Highlights

Increase Confidence        
Absolute method for robust identification and Assays
Simplify Workflows
Platform procedures for flexibility without comprising compliance
Maximize Efficiency
Contacless technology without instrument preparation for optimal versatility and throughput
Access our Free QC Application Library
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Unlock Unparalleled Robustness For Modern Quality Control.

From raw material testing to the release of high-value drug products, NMR can be tuned for both small and large molecules, providing data-rich information that enables a wealth of applications. Deliver intuitive reports with confidence from simple but ultra specific qualitative procedures to complex, multi-attribute quantitative testing with unmatched robustness.

As a primary method with unique capabilities, NMR technology streamlines all steps of the analytical procedure life cycle. By leveraging the modern concept of technology-inherent justifications and platform procedures of the Analytical Quality by Design (AQbD) framework of the recent ICH Q14 and ICH Q2(R2), NMR enables simplified risk management, shorter method development, simplified procedure validation and direct method transfer.

As a contactless, absolute technology, NMR also simplifies routine testing. It delivers absolute values without identical standards while eliminating lengthy system conditioning, cleaning and calibration, shortening time-to-results. Without any solvent consumption, it also helps laboratories to limit waste production for modern, compliant, sustainable quality control.

End-to-end solutions for compliant testing

Our comprehensive solutions for quality control deliver high-end systems with disruptive tools for seamless implementation and routine use of compliant methods, that adapt to each laboratory requirements and topologies.

The new Advanced Chemical Profiling software allows fully automated, end-to-end analytical workflows from simple identification testing to the most demanding quantitative NMR assays. Methods can be implemented in just few steps in a unified, integrated interface and provide true hands-off operations for routine operations. It eliminates time-consuming manual data analysis while providing the level of flexibility required by QC laboratories for maximal efficiency and robustness.

With built-in support for compliance with our GxP kits, our solutions can be implemented seamlessly in GMP- and GLP-regulated environments, delivering all the benefits of NMR to non-expert laboratories for efficient, automated and trustworthy procedures.

Webinars

banner-webinar-Emerging NMR Solutions for the Pharmaceutical Industry
ON DEMAND SESSION – November 24, 2021

Emerging NMR Solutions for the Pharmaceutical Industry

In this virtual roundtable, experts explore the uses of nuclear magnetic resonance (NMR) in the pharmaceutical industry, aimed at addressing the role of NMR in the development and manufacture of small molecule and biological therapeutics.
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ON DEMAND SESSION - September 1, 2021

NMR in Quality Control and Manufacturing

In this one-hour roundtable, we will discuss the current role of NMR in Quality Control and Manufacturing.
Discovery of small molecules that target RNA. NMR is the method of choice.
ON DEMAND SESSION – June 18, 2024

Validation and implementation of qNMR as platform methods of oligonucleotides and peptides

The content of e.g peptides or oligonucleotides in a sample (solid or liquid) is of importance in many aspects. For peptides traditional methods like Kjeldahl nitrogen determination, elementary analysis (EA), and amino acid analysis (AAA), requires break down of the protein at harsh conditions to determine the protein content. For oligonucleotides one of the most widely used techniques for quantification is ultraviolet (UV) spectroscopy.
Discovery of small molecules that target RNA. NMR is the method of choice.
On Demand Session - March 18, 2025

Paradigm Shift in Analytical Development and Quality Control

Learn about modern and robust solutions for QC to streamline procedure life cycle management and meet the evolving regulatory framework. Discover unique GMP-compliant end-to-end solutions for qualitative and quantitative applications, from raw material testing to the control of high-value finished products.
Discovery of small molecules that target RNA. NMR is the method of choice.
On Demand Session - February 26, 2025

Explore automated workflows with the Fourier 80 benchtop NMR spectrometer

The hardware: This webinar will provide an overview of Bruker’s Fourier 80 compact and cryogen-free benchtop NMR spectrometer highlighting its features, capabilities, and available accessories.


Support

LabScape

Service & Life Cycle Support for Magnetic Resonance and Preclinical Imaging

Bruker’s commitment to provide customers with unparalleled help throughout the buying cycle, from initial inquiry to evaluation, installation, and the lifetime of the instrument is now characterized by the LabScape service concept.

LabScape Maintenance Agreements, On-Site On-Demand and Enhance Your Lab are designed to offer a new approach to maintenance and service for the modern laboratory