MALDI Biotyper for Industrial Application

Identifying Microorganisms by their Molecular Fingerprint

The MALDI Biotyper is acknowledged all over the world as the state-of-the-art system solution for the identification of microorganisms

The MALDI Biotyper identifies microorganisms using MALDI-TOF (Matrix Assisted Laser Desorption Ionization – Time of Flight) Mass Spectrometry to determine the unique protein fingerprint of an organism. The characteristic pattern spectrum pattern of this protein fingerprint is used to reliably and accurately identify a particular microorganism by matching thousands of reference spectra of microorganism strains.

Up-to-date and traceable

The integrated library of the MBT software comprises spectra of thousands of strains of, currently, 2969 species including bacteria and fungi (yeast and mold). The library is continuously maintained and updated according to strict quality controlled procedures. Spectra are determined from:

  • isolates from collaborating partners
  • round robin strains
  • ISO 9001: certified strain collection isolates

The best technology from the experts in mass spectrometry

As the leader in MALDI-TOF technology it is of great importance to Bruker to design robust, compact high performance platforms intended for extensive and routine use in the microbiology laboratory.

MALDI Biotyper is a modular system designed to be configured according to individual laboratory needs. Bruker offers laboratories the choice of the microbial MALDI-TOF mass spectrometer that best fits their needs:

  • The MALDI Biotyper based on the microflexTM LT/SH MALDI TOF mass spectrometer with N2 laser providing 60 Hz repetition rate.
  • The MALDI Biotyper based on the microflex LT/SH “smart” MALDI TOF mass spectrometer with Bruker’s proprietary smartbeamTM solid state laser technology providing 200 Hz repetition rate

True bench-top solution

MALDI Biotyper is a low-noise operating system with low weight, requiring less than 3 feet of counter space meeting laboratory needs for compact system solutions.

Easy to use

Intuitive software, WhisperMode™ for silent and pleasant operation.

High sensitivity

Resolution and sensitivity of the spectrometers are tailored to the needs of microbiologists. With the most sensitive detector technology available (FlashDetector™), users benefit from having the same high performance technology as large research-grade instruments without the need for unnecessary long and bulky instrument flight tubes.

Fast and gentle

With Smart Spectra AcquisitionTM, data generation is accelerated by minimizing the number of shots per sample needed to generate a signal. MALDI Biotyper systems offer the highest throughput for MALDI-TOF microbiology testing.

High accuracy

Greater than 98 percent accuracy compared to reference method 16S RNA sequencing in a multi-site clinical trial.

Highly reproducible results - run-to-run

The quick and simple Bacterial Test Standard (BTS) quality check performed before each run provides the highest standard of reproducibility.

Continuous operation

The self-cleaning MALDI PerpetualTM ion source permits continuous high performance with minimized maintenance requirements. Cleaning of the source using the separate IR-laser is performed easily under operator control.

Open Microbiology Concept

Open system with proven connectivity to a wide variety of lab devices.

Significantly reduces costs

Studies show MALDI Biotyper costs are as much as 80 percent lower than conventional microbiology methods.