EPR Software 1154x400

NMR based Metabolomics Package

IVDr means high-performance bodyfluid analysis. To fully benefit we offer the following
Software solutions at 20% discount for a limited period:

1. B.I.Methods 2.0 : Highly standardized and fully automated NMR methods for bodyfluid analysis at 600 MHz

  • SOPs for preparation and measurement of bodyfluids e.g. Urine, Plasma, Serum, CSF and Methanol-extracts
  • Includes advanced system suitability, quality control, calibration and validation functionalities
  • Prerequisite for all data analysis tools
  • First step in updating to Avance IVDr platform

2. B.I.LISA 1.0 RUO* : Fast and reliable determination of Lipoprotein Subclasses and subfractions in Plasma or Serum

  • Lipoprotein Subclass Analysis in Plasma/Serum with > 110 parameters from ultracentrifugation
  • Includes Cholesterol, Free Cholesterol, Triglycerides, Phopholipids, main and sub-fractions
  • Includes Particles Numbers, Apo-A1, Apo-A2 and ApoB

3. B.I.QUANT-PS 2.0 RUO* : Highly reliable and automated quantification of small molecule in Plasma or Serum

  • Simultaneous absolute quantification of 40 free metabolites from 9 different chemical class in Plasma/Serum
  • Improved quantification scheme and fit visualisation
  • Concentration ranges occurring in most human plasma/serum samples
  • Results obtained on the same experiment as B.I.LISA

4. B.I.QUANT-UR 1.1 RUO* : Highly reliable and automated quantification of small molecule in Urine

  • Simultaneous absolute and relative quantification of small molecules from 12 different chemical class in urine with improved results interpretation routines
  • 3 versions: Basic 50 metabolites (children & adults), Extended 150 metabolites (neonates, children & adults)
  • Concentration ranges occurring in most human plasma/serum samples

5. B.I.Biobank-QC 1.0 RUO* : Automated Quality Control of incoming samples for storage in Biobanks

  • Extended Quality Control for incoming urine or plasma/serum in biobanks
  • Validate type of bodyfluid, check contaminations, degradation state, unreported drugs, disease markers
  • extensive documentation with traffic light system
  • same experiment as for the analysis tools B.I.LISA, B.I.QUANT-PS2.0 and B.I.QUANT-UR1.1 b/e/ne

6. B.I.IEM-Panel 1.0 RUO*: Automated Intelligence for interpretation of NMR urinary findings in Inborn Errors of Metabolism research

  • Using comprehensive Inborn Error of Metabolism knowledgebase to convert urine quantification result (B.I.QUANT-UR1.1) into list of ranked potential diseases

7. AMIX 4.0: Powerful program providing many integrated routines for statistical and spectroscopic analyses

  • Dedicated programm for metabolomics analysis
  • Includes comparison of multiple spectra, matching of bodyfluid spectra with pure compound spectra (BBIOREFCODE), statistics toolbox

8. BBIOREFCODE: Get more information on further metabolites with Bruker’s Biofluid Reference Compound spectral database

  • 800 metabolites: 1D-spectra at 11 pH values and 2D-spectra at 3 pH values
  • Efficient visual inspection to identify unknown signals
  • Automatic matching routines for 1D and 2D using AMIX 4.0

Please contact your local sales person for detailed information, pricing and requirements

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