Biospec 117 11 USR

The 117/11 BioSpec opens the door to ultra-high-field MRI. Its exceptional gradient strength and slew rate make even the most challenging studies possible. The BioSpec 117/11 has a streamlined operation for examinations of mice brain, head, and body. It can be equipped with the MRI CryoProbe to increase sensitivity even further and together with the gradient strength of up to 1000 mT/m, highest resolution is achieved. It is built with nitrogen-free Ultra Shielded and helium Refrigerated (US/R) magnet technology for long service intervals.

Application BioSpec 117 11

Vessel abnormalities, visible in TOF FLASH can depend on severity of rectal inflammation in mouse KO model

Courtesy: Y. Yoshioka, Osaka University, Osaka, Japan

Highlights

  • Nitrogen-free Ultra Shielded and helium Refrigerated (US/R) magnet technology with long service intervals
  • Full second and third order high power shim channels guarantee optimal performance for spectroscopy and imaging
  • Crisp and highly resolved images with native gradient strength of 740 mT/m, upgradable to 1000 mT/m
  • Slew rate: 9000 T/m/s  
  • Gradient inner diameter: 60 mm
  • Actively shielded gradient system
  • Integrated shim coils for optimal field homogeneity
  • In-house development and production of all key components (software, magnet, gradient, spectrometer, RF coils) ensures the best performance

Magnet

  • Field strength:  11.7 Tesla 
  • Bore diameter: 11 cm  
  • Magnet technology:  Nitrogen-free Ultra Shielded and helium Refrigerated (US/R)  

Gradients

  • Gradient inner diameter: 60 mm 
  • Gradient strength: 740 mT/m (1000 mT/m with high power option
  • Slew rate: 9000 T/m/s
  • Actively shielded gradient system
  • Integrated shim coils for optimal field homogeneity

 

Electronics

  • AVANCE NEO electronics enabling both MRI and MRS applications
  • The digital signal processing system operates at 1H resonance frequency of 500 MHz and utilizes digital filtering, digital quadrature demodulation as well as digital controls for RF amplitude stabilization for superior resolution and image quality
  • Real-time spectrometer control for optimization of acquisition parameters during scan
  • Up to 16 digital receive channels

RF Coils

  • MRI CryoProbe for for exceptional increase in sensitivity
  • Volume resonators ranging from 15 mm up to 35 mm  inner diameter
  • Multi-channel array coils enable parallel imaging applications
  • Active RF decoupling for independent operation of transmit and receive coils
  • Integrated preamplifiers guarantee optimal sensitivity over a large dynamic range
  • Hardware recognition of RF coils automatically configures all relevant parameters


Software

  • Over 100 validated and ready to use in vivo protocols and scan programs for mice and rats
  • Fully-featured ParaVision® preclinical user interface for streamlined workflow and most powerful analysis
  • MRI sequence portfolio of more than 1,000 sequence variations, including wireless cardiac imaging using navigator based IntraGate methods with a choice of cartesian or radial readout, as well as short echo time imaging, such as UTE and ZTE
Mouse Spinal

Mouse spinal cord tractography at lumber L3-L6 at 11.7T

Courtesy: Prof. Y. Yoshioka, Osaka Univiversity, Osaka, Japan 

Fixed mouse brain

Fixed mouse brain without any contrast reagents at 11.7T

Courtesy of Prof. Y. Yoshioka, Osaka University, Osaka, Japan

Mouse liver

Mouse liver PRESS spectroscopy without water suppression at 11.7T

Courtesy: Prof. Y. Yoshioka, Osaka University, Osaka, Japan 

Manganese

Manganese enhanced MRI rat fixed brain at 11.7T

Courtesy: Prof. Y. Yoshioka, Osaka University, Osaka, Japan