AFM 模式

力-距离测量

针对个别力相互作用进行表征

力-距离曲线。趋近曲线（红色）和趋远曲线（蓝色）如右所示。请注意，总接触力取决于粘附力以及所施加的载荷。

配体与受体分子结合的结合力通常会对生物系统产生深远的下游效应。这种相互作用在细胞信号转导和药物研究等领域也非常重要。借助力-距测量，研究人员能够对探针在接近样品表面和从样品表面收回时的吸引力和排斥力进行研究。通过将感兴趣的分子附着在探针针尖可以获得其他数据。

力-距离技术通常用于研究基本的相互作用力、纳米尺度的粘附和弹性响应、结合力、胶体研究和化学感测。力-距离测量只是布鲁克纳米力学全面解决方案中的一种技术，此外还有PeakForceQNM®和定量Force Volume成像。

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