PET/CT Si78

Two best in class imaging technologies, combined in one instrument. This complete solution was designed with the researcher in mind to offer unlimited possibilities for in vivo preclinical imaging applications.

Bruker's Full Field of View Accuracy SiPM PET technology, are now combined with low dose - high throughput SkyScan micro-CT. Offering a unique instrument, with supreme PET/CT imaging performance, the PET/CT Si78.

The PET/CT Si78 features homogeneous, high-resolution, and quantitative PET/CT imaging with a large field of view of 80 x up to 200 mm.

The unique low dose X-ray technology, combined with ultra-fast full body 3D CT scanning, the familiar ParaVision 360 software and a high-precision motorized animal transport system, simplifies your workflow.

• Total Body PET for mice and rats
• Full Field-of-View PET quantitative accuracy
• Low-dose, high-contrast fast CT scans for longitudinal PET/CT studies, and excellent performance in demanding bone, cardiac, and lung applications
• ParaVision 360 preclinical imaging workflows using validated multi-modal in vivo protocols and scan programs
• Interactive scan planning, introducing PET and CT preclinical imaging methods and interactive geometry editors
• Accurate touch screen animal positioning
• Double-sided and fully open access to the imaging gantry with a minimum distance to the PET FOV for kinetic tracer studies
• Single click, auto connect animal cradles for mice and rats, including anesthesia supply, animal warming, respiration and ECG sensors and gas exhaust sensors

• Interactive scan planning, introducing PET and CT preclinical imaging methods and interactive geometry editors
• Accurate touch screen animal positioning
• Double-sided and fully open access to the imaging gantry with a minimum distance to the PET FOV for kinetic tracer studies

Single click, auto connect animal cradles for mice and rats, including anesthesia supply, animal warming, respiration and ECG sensors and gas exhaust sensors

• Patented continuous LYSO crystals, unrestrained by discrete layers, and high-resolution depth-of-interaction technology enable precise 3D localization of events. This precise event localization results in  constant and high spatial resolution when moving out of the center of the PET Field-of-View.
• Consistent and reproducible tracer quantification within the entire FOV, regardless of object size, position and activity is enabled by the homogeneous spatial resolution.
• Ultra-fast reconstruction (under 1min) using GPU reconstruction and MLEM reconstruction.
• Exceptional count rate performance combined with 12% sensitivity for dynamic and gated studies for high temporal resolution and superior image quality.

• Microfocus X-ray source with adjustable energy and automatic filter setting allows optimized scanning protocol with minimized applied doses.
• Fast and sensitive flat-panel detector resolving dynamics of mouse heart and lungs activities.
• Patented spatial beam shaper reduces the X- ray dose by 2-5 times without degradation of image quality.
• Accelerated GPU reconstruction supports beam hardening correction, misalignment compensation, ring artifact removal and many other options.
• On-screen dose meter indicates applied dose to the animal based on information from individual analysis of X-ray images.

Full field of view and accuracy offers real, homogeneous sub-millimetric volumetric PET resolution and quantification in all three axes, in the entire field of view. This is possible due continuous crystal detectors with SiPM technology and true depth of interaction 3D precision equivalent to 10+ layer pixelated crystal detectors.

• Microfocus X-ray source with adjustable energy and automatic filter setting allows optimized scanning protocol with minimized applied doses
• Fast and sensitive flat-panel detector resolving dynamics of mouse heart and lungs activities
• Patented spatial beam shaper reduces the X- ray dose by 2-5 times without degradation of image quality
• Accelerated GPU reconstruction supports beam hardening correction, misalignment compensation, ring artifact removal and many other options
• On-screen dose meter indicates applied dose to the animal based on information from individual analysis of X-ray images

Bruker animal cradles are designed for easy workflows in the preclinical imaging lab. Animal life support and PET tracer application equipment can be interfaced to the main instrument with a single clip on action, with dedicated ports for:

• Anesthesia systems
• Life monitoring systems
• PET catheter feedthroughs
• Cardiac or respiration gating

Single click benchtop prep station is available, facilitating preparation of the animal prior imaging.

Fully integrated ParaVision 360. ParaVision 360 enters the world of seamless multimodal imaging. Modern imaging laboratories using PET, CT or MR instruments profit from the fully integrated common imaging platform.

More Information on PET/CT SI78 and Applications: