Bruker at ASMS 2024

June 2 - 6, 2024

Anaheim, CA, USA

Where Innovation Takes Center Stage

Prepare to be transported to the heart of innovation at ASMS 2024 with Bruker. Experience cutting-edge advancements in mass spectrometry technology while soaking in California's vibrant spirit.

eXceed Symposia 2024 | Breakfast Workshops | Booth #312

Explore the latest breakthroughs in Bruker mass spectrometry across:

  • 4D-Proteomics™
  • 4D-Lipidomics™ and 4D-Metabolomics™
  • Imaging including SpatialOMx®
  • Pharma and Biopharma
  • Applied Markets — food and beverage, environmental testing, and industrial applications

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eXceed Symposia
June 2, 2024
8:30 am – 1:00 pm PST
Westin Anaheim
1030 West Katella Avenue, Anaheim, CA, USA
Plenary session: Annabella Ballroom A-B

Albert Heck
Ph.D., Professor of Chemistry and Pharmaceutical Sciences, Utrecht University and Scientific Director, Netherlands Proteomics Center, Utrecht, Netherlands

Blaine R. Roberts
Ph.D., Associate Professor and Principal Investigator, Emory University School of Medicine, Atlanta, GA, USA

Lingjun Li
Ph.D., Vilas Distinguished Achievement Professor, Charles Melbourne Johnson Distinguished Chair Professor, University of Wisconsin-Madison, WI, USA

8:30 am Welcome and introduction 
Rohan A. Thakur, Ph.D., President, Life Sciences Mass Spectrometry Division, Bruker, Fällanden, Switzerland

8:50 am It is in our blood, protein-centric approaches to tackle your antibody repertoires
Albert Heck, Ph.D., Professor, Chemistry and Pharmaceutical Sciences, Utrecht University and Scientific Director, Netherlands Proteomics Center, Utrecht, Netherlands

9.15 am Keynote speaker talk
Blaine R. Roberts, Ph.D., Associate Professor and Principal Investigator, Emory University School of Medicine, Atlanta, GA, USA

9.40 am Probing Cellular Heterogeneity via Spatially Resolved Omics and Mass Spectrometry Imaging
Lingjun Li, Ph.D., Vilas Distinguished Achievement Professor, Charles Melbourne Johnson Distinguished Chair Professor, University of Wisconsin-Madison, WI, USA

10.05 am After the plenary session, the meeting will break into three parallel sessions.  

Breakout Session Proteomics
Annabella Ballrooms A-B

Nikolai Slavov
Ph.D., Director, Parallel Squared Technology Institute and Professor, Northeastern University, Boston, MA, USA

Roman Fischer
Ph.D., Associate Professor, University of Oxford, Centre for Medicines Discovery (CMD), Target Discovery Institute (TDI), CAMS Oxford Institute (COI), Oxford, UK

Lindsay Pino
Ph.D., Co-Founder and CTO, Talus Bio, Seattle, WA, USA

10:30 am Introduction
Daniel Hornburg, Ph.D., Vice President, Biomarkers and Precision Medicine, Bruker Scientific LLC, Billerica, MA, USA

10:45 am High throughput protein analysis of single cells and subcellular organelles reveals regulatory principles
Nikolai Slavov, Ph.D., Director, Parallel Squared Technology Institute and Professor, Northeastern University, Boston, MA, USA

11:10 am Precision proteomics in human disease
Roman Fischer, Ph.D., Associate Professor, University of Oxford, Centre for Medicines Discovery (CMD), Target Discovery Institute (TDI), CAMS Oxford Institute (COI), Oxford, UK

11:35 am Profiling oncogenic transcription factors using mass spectrometry proteomics
Lindsay Pino, Ph.D., Co-Founder and CTO, Talus Bio, Seattle, WA, USA

12:00 pm Break

12:15 pm Customer talk 4
Harris Bell-Temin, Ph.D., Associate Director, Proteomics at Johnson & Johnson Innovative Medicine, Boston, MA, USA

12:40 Customer talk 5
Ileana Cristea, Ph.D., Associate Professor, Princeton University, NJ, USA

Breakout Session MALDI Imaging/SpatialOMX
Annabella Ballroom C-D

Carsten Hopf
Ph.D., Professor and Head, CeMOS, Mannheim - M2Aind Industry Consortium, Mannheim, Germany

Mark Lim
Ph.D., Executive VP and CSO, AmberGen, Waltham, MA, USA

Brian Hoffman
Ph.D., Director, Mass Spectrometry Services and Protein Sciences, The Jackson Laboratory, Bar Harbor, ME, USA

Jake Dressman
Graduate Student, Medical University of South Carolina, Charleston, SC, USA

Mengze Stettler-Zhang
Ph.D., Joint Doctoral Researcher, University of Zürich and ETH Zurich, Zurich, Switzerland

Erin Seeley
Ph.D., Director, Mass Spectrometry Imaging Facility, University of Texas, Austin, TX, USA

10:30 am Introduction
Kate Stumpo, Ph.D., Senior Market Manager Imaging Global, Bruker Scientific LLC, Billerica, MA, USA

10:35 am Customer talk 1
Carsten Hopf, Ph.D., Professor and Head, CeMOS, Mannheim - M2Aind Industry Consortium, Mannheim, Germany

10:55 am Unparalleled Spatial Multiomics at the Tissue and Single-Cell Level with MALDI HiPLEX-IHC
Mark Lim, Ph.D., Executive VP and CSO, AmberGen, Waltham, MA, USA

11:15 am Integrated multi-omics approaches for the analysis of lung adenocarcinoma
Brian Hoffman, Ph.D., Director, Mass Spectrometry Services and Protein Sciences, The Jackson Laboratory, Bar Harbor, ME, USA

11:35 pm Single-Cell Omni-Omics (SC-OO): Analysis of Captured Single Cells by multi-modal MALDI-IMS
Jake Dressman, Graduate Student, Medical University of South Carolina, Charleston, SC, USA

12:00 pm Break

12:15 pm 120-plex MALDI-IHC recapitulates tissue structures and reveals diverse spatial features of endometrial cancer
Mengze Stettler-Zhang, Ph.D., Joint Doctoral Researcher, University of Zurich and ETH Zurich, Zurich, Switzerland

12:35 pm Integration of Multiplexed Multi-omic Imaging for a Deeper Understanding of the Tumor Microenvironment
Erin Seeley, Ph.D., Director, Mass Spectrometry Imaging Facility, University of Texas, Austin, TX, USA

Breakout Session Multiomics
Gloriana A-C

Hans Wessels
Ph.D., Proteomics Scientist, Radboud University, Nijmegen, Netherlands

10:30 am Introduction
Erica Forsberg, Ph.D., Vice President, Metabolomics, AMER and APAC, Bruker Scientific LLC, Billerica, MA, USA
Matt Lewis, Ph.D., Vice President, Metabolomics, EMEA, Bruker UK Ltd., Coventry, UK
Klaus Lindpaintner, Ph.D., Vice President, Glycobiology Solutions, Bruker Scientific LLC, Billerica, MA, USA

10:45 am Customer talk 1
Hans Wessels, Ph.D., Proteomics Scientist, Radboud University, Nijmegen, Netherlands

11:10 am 4D-Lipidomics™ - enhanced deep lipidome coverage and profiling in clinical specimens
Laura Bindila, Ph.D., Head of Clinical Lipidomics Unit, Institute of Physiological Chemistry, University Medical Center Mainz, Germany

11:35 am Advances in Leveraging Unannotated Data and Machine Learning for Metabolite Structure Prediction
David Healey, Vice President of Data Science and Machine Learning, Enveda Biosciences, Salt Lake City, USA

12:00 pm Break

12:15 pm Customer talk 4
TBD 

12:40 Customer talk 5
TBD

Breakfast Workshops

Breakfast Workshop Proteomics
Monday, June 3, 2024
7:00 am PST

Anaheim Convention Center, 800 W Katella Ave, Anaheim, CA, USA
Room: 202AB

Discover new biomedical insights through the lens of 4D-Proteomics™. From single cell to neoantigen discovery and large scale plasma studies, we will discuss end-to-end solutions that provide critical insights into cellular processes and support personalized medicine research.

Download the agenda here

 

Breakfast Workshop Metabolomics/Lipidomics
Monday, June 3, 2024
7:00 am PST

Anaheim Convention Center, 800 W Katella Ave, Anaheim, CA, USA
Room: 208AB

At our Breakfast Workshop, we’ll delve into the fascinating world of metabolomics and lipidomics that unlock the secrets of cellular processes through the comprehensive analysis of metabolites and lipids. These fields are revolutionizing our understanding of the biochemical pathways that fuel our bodies, much like a nutritious breakfast powers our day. Join us as we explore how these molecular insights are shaping the way we understand biological mechanisms of health and disease.

Download the agenda here

 

Breakfast Workshop Pharma
Tuesday, June 4, 2024
7:00 am PST

Anaheim Convention Center, 800 W Katella Ave, Anaheim, CA, USA
Room: 202AB

Join your Pharma colleagues and learn about the latest high sensitivity applications for advancing drug discovery.

Download the agenda here

 

Breakfast Workshop MALDI Imaging/SpatialOMX
Wednesday, June 5, 2024
7:00 am PST

Anaheim Convention Center, 800 W Katella Ave, Anaheim, CA, USA
Room: 202AB

You no longer have to dream about how to make your MALDI Imaging methods multimodal. Our breakfast workshop will feature cutting edge research for spatial analysis.

Download the agenda here

Applied Breakfast Workshops

Innovative Chromatography-Free Analytical Techniques for Advanced Polymer Characterization and Manufacturing Optimization
Monday June 3, 2024
7:00 am - 8:00 am

Anaheim Convention Center, 800 W Katella Ave, Anaheim, CA, USA
Room: 210D 

Mass spectrometry (MS) plays a crucial role in polymer analysis, enabling comprehensive assessment of structure, composition, additives, and molecular weight distribution. However, traditional MS methods often necessitate chromatography for sample separation.  This workshop focuses on the streamlined various Chromatography FREE approaches including DART, which analyzes complex polymeric materials without prior preparation, utilizing hot metastable He atoms to induce thermal desorption and degradation, followed by ionization for analysis of stable materials. Case studies involving automotive tires and macro-/nano-plastics from Northeast Ohio illustrate the efficacy of DART-MS. Additionally, MALDI-MS, another chromatography-free MS method, is discussed for addressing performance issues in complex polyolefin-based materials, offering insights into reaction mechanisms and architectural distributions crucial for process optimization in manufacturing.

Download the agenda here

 

Total PFAS coverage using novel targeted and non-targeted workflows on an LC/TQ and timsTOF
Tuesday, June 4, 2024
7:00 am - 8:00 am

Anaheim Convention Center, 800 W Katella Ave, Anaheim, CA, USA
Room: 210D

PFAS, persistent chemicals used in consumer products since the 1940s, pose significant risks to both humans and the environment due to their persistent, bio-accumulative, and toxic properties. EPA regulations exist to monitor selected PFAS compounds, but the estimated total of 15,000 PFAS compounds, complicates comprehensive analysis. Two workflows are presented: targeted analysis using a highly sensitive triple quadrupole for routine monitoring, exceeding EPA regulations, and a non-targeted approach combining trapped ion mobility spectrometry (TIMS) with UHPLC-HRMS for broader PFAS detection and annotation of unknown PFAS using smart software tools. These methods aim to improve detection capabilities and understanding of PFAS exposure for better public health and environmental protection.

Download the agenda here

 

Rapid and Dynamic Quantitative Screening of Synthetic Cannabinoids with DART-MS Analysis: A Collaborative Case Study
Wednesday, June 5, 2024
7:00 am - 8:00 am

Anaheim Convention Center, 800 W Katella Ave, Anaheim, CA, USA
Room: 210D

Join us for a presentation of a novel rapid and quantitative screening approach for detection and measurement of 16 synthetic cannabinoids using DART-MS. Our novel approach resolves drawbacks associated with traditional immunoassay-based detection, such as cross-reactivity and low sensitivity. Through comparative validation with LC-MS using confirmed positive urine samples, the DART-MS screening method demonstrates high selectivity and accuracy. With a throughput of under 30 seconds per sample, this approach offers a cost-effective and efficient solution for detecting synthetic cannabinoids in urine samples.

Download the agenda here

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eXceed Symposia - June 2, 2024
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