TopSpin

TopSpin® is Bruker's standard NMR software used in a wide range of workflows. Starting with the control of the spectrometer up to the processing and analysis of multidimensional NMR spectra. The acquisition interface provides easy access to vast NMR experiment libraries including standard Bruker pulse sequences and user generated experiment libraries, for both routine and advanced NMR users. TopSpin provides numerous options for setting up and optimizing NMR experiments, making the setup of sophisticated experiments simple and efficient. For users who must be compliant with the GxP regulations, the software supports the various principles of data integrity. 

TopSpin® offers a fully workflow-oriented user interface and leverages the latest 64-bit features of modern Windows / AlmaLinux / macOS operating systems for optimal performance. The software is designed to accelerate the operation and throughput of sample analysis for increased cost efficiency.

Get an Industrial / Pharma processing license:

Get a free academic processing license:

Meet TopChat, your AI assistant within the TopSpin® NMR software environment. Need help with an acquisition? Looking for the right command or functionality? Or have a question about your NMR workflow? TopChat provides guidance directly within TopSpin, giving users convenient access to information when and where they need it.

From answering questions to helping users navigate TopSpin’s extensive capabilities, TopChat brings AI-powered assistance into the everyday NMR workflow, so users can spend less time searching for information and more time focusing on their work.

• AI-assisted guidance with TopChat, providing direct access to TopSpin knowledge, multilingual support, traceable sources, and the option to extend the knowledge base with your own documentation.
• Assisted NMR acquisition, including experiment selection, advanced non-uniform sampling (NUS), bioTop, and the TopSolids method development environment.
• Flexible task automation and scripting for customized NMR workflows.
• GxP-ready functionality supporting data integrity and compliance with audit trails, electronic signatures, and auto-archiving.
• Unlimited offline processing for flexible NMR data processing and analysis.
• Comprehensive NMR analysis tools, including structure elucidation with CMC-se™, small molecule characterization, solid-state NMR, and dynamic NMR.
• Educational tools and resources to support the training of future NMR users.

• One environment from acquisition to analysis, with comprehensive tools for controlling the spectrometer, acquiring, processing, displaying, and analyzing NMR data.
• Expertise at your fingertips with TopChat, helping users find answers, understand TopSpin functionality and get guidance on NMR workflows without leaving the software environment. TopChat supports both quick lookups and broader questions.
• Efficient workflows for users at different experience levels, combining guided functionality for less experienced users with the flexibility and depth required by NMR experts.
• Greater productivity and instrument utilization through streamlined workflows, automation, and efficient sample processing.

Supported Operating Systems

• 64-bit operating system required for TopSpin
• Windows 10, 11 or Alma Linux 9.4 required for spectrometer control. CentOS 7 is also supported, however it reaches its end of live at June 30 2024.
• Processing version of TopSpin are available for Windows 10, 11 and macOS
• Detailed list of supported operating systems is available here (requires login)

Detailed information about licences and more can be found in the TopSpin FAQ