NMR Software


Get the most out of your Bruker NMR instrument with TopSpin software for both routine and advanced NMR acquisition and analysis.

New TopSpin 4.3.0 release is now available and offers new features including:

  • Extended operating system support
    - Alma Linux 9.1 is the new Linux operating system for spectrometer control. It replaces CentOS 7 whose support ends in 2024.
    - Windows 11 is now supported for spectrometer control.
  • Data browser improvements

TopSpin 4.3 for spectrometer control was tested and validated for Windows 10 and 11, CentOS 7, and Alma Linux 9.1.

Smart Acquisition
Get high quality data in short time due to effective workflows.
Advanced Processing
Profit from fast and flexible algorithms for processing and analysis of NMR data/spectra.
Modular Application Platform

Leverage a wide range of add-ons.


TopSpin® is Bruker's standard NMR software used in a wide range of workflows. Starting with the control of the spectrometer up to the processing and analysis of multidimensional NMR spectra. The acquisition interface provides easy access to vast NMR experiment libraries including standard Bruker pulse sequences and user generated experiment libraries, for both routine and advanced NMR users. TopSpin provides numerous options for setting up and optimizing NMR experiments, making the setup of sophisticated experiments simple and efficient. For users who must be compliant with the GxP regulations, the software supports the various principles of data integrity. 

TopSpin® offers a fully workflow-oriented user interface and leverages the latest 64-bit features of modern Windows / CentOS / macOS operating systems for optimal performance. The software is designed to accelerate the operation and throughput of sample analysis for increased cost efficiency.

Get an Industrial / Pharma processing license:


Get a free academic processing license:

TopSpin Features

  • Assisted acquisition including experiment selector, advanced non-uniform sampling methods (NUS), bioTop, and TopSolids Method development environment
  • Flexible task automation (scripting)
  • GxP ready: supports compliance with audit trails, electronic signatures, auto-archiving
  • Unlimited offline processing capabilities
  • Comprehensive analysis tools available (structure elucidation of small molecules with CMC-seTM, small molecule characterization, solid-state NMR, including dynamic NMR)
  • Educational package to train future NMR users


  • TopSpin provides full control of your spectrometer.
  • Extensive functionality for processing, displaying and analyses in one tool – time saving and without loss of accuracy.
  • The ideal tool for NMR experts as well as for NMR novices
  • Higher sample throughput and therefore higher cost efficiency


Supported Operating Systems

  • 64-bit operating system required for TopSpin 4
  • Windows 10 or CentOS 7 required for spectrometer control
  • Processing version of TopSpin available for Windows 10, CentOS 7, and macOS
  • Detailed list of supported operating systems available

Detailed information about licences and more can be found in the TopSpin FAQ

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Service & Life Cycle Support for Magnetic Resonance and Preclinical Imaging

Bruker’s commitment to provide customers with unparalleled help throughout the buying cycle, from initial inquiry to evaluation, installation, and the lifetime of the instrument is now characterized by the LabScape service concept.

LabScape Maintenance Agreements, On-Site On-Demand and Enhance Your Lab are designed to offer a new approach to maintenance and service for the modern laboratory

Connexus – Connecting Labs

Connexus® brings clients in need of advanced analytical techniques together with labs that have available capacity on their high-tech scientific NMR instruments*.

*The new Bruker BioSpin online platform Connexus is available in selected European countries