TopSpin
TopSpin 5 – Streamline Tasks. Focus on Your Science
TopSpin 5.1.0 takes the next step in the evolution of the TopSpin 5 platform, bringing further improvements in usability, automation, stability, and NMR workflow efficiency. Building on the introduction of SpinPilot and Bruker BioSpin IAM in TopSpin 5.0.0, the new release further refines acquisition, processing, and spectrometer control for a more streamlined day-to-day user experience.
Highlights of TopSpin 5.1.0 include:
- TopChat provides AI-powered assistance for working with TopSpin, from answering questions to supporting NMR workflows and data analysis.
- Further enhancements to SpinPilot acquisition and automation workflows
- Improved usability and workflow efficiency throughout TopSpin
- Enhancements to acquisition, processing, and spectrometer control
- Continued integration of Bruker BioSpin Identity and Access Management (IAM)
- Improved stability and reliability based on feedback from TopSpin 5.0.0
- Numerous additional enhancements and bug fixes, documented in the TopSpin 5.1.0 release letter
TopSpin 5.1.0 for Spectrometer Control has been tested and validated on Windows 11 and Alma Linux 9.8.
Leverage a wide range of add-ons.
TopSpin® is Bruker's standard NMR software used in a wide range of workflows. Starting with the control of the spectrometer up to the processing and analysis of multidimensional NMR spectra. The acquisition interface provides easy access to vast NMR experiment libraries including standard Bruker pulse sequences and user generated experiment libraries, for both routine and advanced NMR users. TopSpin provides numerous options for setting up and optimizing NMR experiments, making the setup of sophisticated experiments simple and efficient. For users who must be compliant with the GxP regulations, the software supports the various principles of data integrity.
TopSpin® offers a fully workflow-oriented user interface and leverages the latest 64-bit features of modern Windows / AlmaLinux / macOS operating systems for optimal performance. The software is designed to accelerate the operation and throughput of sample analysis for increased cost efficiency.
Get an Industrial / Pharma processing license:
Get a free academic processing license:
TopSpin Goes AI
Meet TopChat, your AI assistant within the TopSpin® NMR software environment. Need help with an acquisition? Looking for the right command or functionality? Or have a question about your NMR workflow? TopChat provides guidance directly within TopSpin, giving users convenient access to information when and where they need it.
From answering questions to helping users navigate TopSpin’s extensive capabilities, TopChat brings AI-powered assistance into the everyday NMR workflow, so users can spend less time searching for information and more time focusing on their work.
TopSpin Features
- AI-assisted guidance with TopChat, providing direct access to TopSpin knowledge, multilingual support, traceable sources, and the option to extend the knowledge base with your own documentation.
- Assisted NMR acquisition, including experiment selection, advanced non-uniform sampling (NUS), bioTop, and the TopSolids method development environment.
- Flexible task automation and scripting for customized NMR workflows.
- GxP-ready functionality supporting data integrity and compliance with audit trails, electronic signatures, and auto-archiving.
- Unlimited offline processing for flexible NMR data processing and analysis.
- Comprehensive NMR analysis tools, including structure elucidation with CMC-se™, small molecule characterization, solid-state NMR, and dynamic NMR.
- Educational tools and resources to support the training of future NMR users.
Benefits
- One environment from acquisition to analysis, with comprehensive tools for controlling the spectrometer, acquiring, processing, displaying, and analyzing NMR data.
- Expertise at your fingertips with TopChat, helping users find answers, understand TopSpin functionality and get guidance on NMR workflows without leaving the software environment. TopChat supports both quick lookups and broader questions.
- Efficient workflows for users at different experience levels, combining guided functionality for less experienced users with the flexibility and depth required by NMR experts.
- Greater productivity and instrument utilization through streamlined workflows, automation, and efficient sample processing.
Specifications
Supported Operating Systems
- 64-bit operating system required for TopSpin
- Windows 10, 11 or Alma Linux 9.4 required for spectrometer control. CentOS 7 is also supported, however it reaches its end of live at June 30 2024.
- Processing version of TopSpin are available for Windows 10, 11 and macOS
- Detailed list of supported operating systems is available here (requires login)
Detailed information about licences and more can be found in the TopSpin FAQ
More Information about TopSpin
- Improving Phase and Baseline Correction: An Extended Algorithm for 1D NMR Spectra in TopSpin 5
- SpinPilot - Automation Software for NMR Labs
- Automatic Peak Picking in 2D NMR Spectra Using Neural Networks
- Accuracy and Long-Term Stability of qNMR Methods with External Calibration
- TopSpin command “sigreg": Deep-Learning Based Signal Region Detection in 1H NMR Spectra
- TopSpin command “apbk": Deep-Learning Based Phase and Baseline Correction of 1H NMR Spectra
- TopSpin command “mldcon": Deep-Learning Based Signal Deconvolution in 1H NMR Spectra
- Exploring 2D HSQC NMR - Application Note
LabScape
Service & Life Cycle Support for Magnetic Resonance and Preclinical Imaging
Bruker’s commitment to provide customers with unparalleled help throughout the buying cycle, from initial inquiry to evaluation, installation, and the lifetime of the instrument is now characterized by the LabScape service concept.
LabScape Maintenance Agreements, On-Site On-Demand and Enhance Your Lab are designed to offer a new approach to maintenance and service for the modern laboratory
