NMR Software


Get the most out of your Bruker NMR instrument with TopSpin software for both routine and advanced NMR acquisition and analysis.

TopSpin 4.4.0 Release Offers Bug Fixes and New Features, Including Extended Operating System Support

Alma Linux 9.3 is the new Linux operating system for spectrometer control. It replaces CentOS 7, which will be retired in 2024.

  • Windows 11 is now also supported for spectrometer control. Windows executable files are digitally signed.
  • Data Browser Enhancements - improved performance, better support for removable media
  • General enhancements such as a pulse program editor with embedded pulse program display, or an enhanced Python interface that supports writing of 1D and 2D spectra.

TopSpin 4.4 for Spectrometer Control has been tested and validated on Windows 10 and 11, CentOS 7, and Alma Linux 9.3.

Smart Acquisition
Get high quality data in short time due to effective workflows.
Advanced Processing
Profit from fast and flexible algorithms for processing and analysis of NMR data/spectra.
Modular Application Platform

Leverage a wide range of add-ons.


TopSpin® is Bruker's standard NMR software used in a wide range of workflows. Starting with the control of the spectrometer up to the processing and analysis of multidimensional NMR spectra. The acquisition interface provides easy access to vast NMR experiment libraries including standard Bruker pulse sequences and user generated experiment libraries, for both routine and advanced NMR users. TopSpin provides numerous options for setting up and optimizing NMR experiments, making the setup of sophisticated experiments simple and efficient. For users who must be compliant with the GxP regulations, the software supports the various principles of data integrity. 

TopSpin® offers a fully workflow-oriented user interface and leverages the latest 64-bit features of modern Windows / CentOS / macOS operating systems for optimal performance. The software is designed to accelerate the operation and throughput of sample analysis for increased cost efficiency.

Get an Industrial / Pharma processing license:


Get a free academic processing license:

TopSpin Features

  • Assisted acquisition including experiment selector, advanced non-uniform sampling methods (NUS), bioTop, and TopSolids Method development environment
  • Flexible task automation (scripting)
  • GxP ready: supports compliance with audit trails, electronic signatures, auto-archiving
  • Unlimited offline processing capabilities
  • Comprehensive analysis tools available (structure elucidation of small molecules with CMC-seTM, small molecule characterization, solid-state NMR, including dynamic NMR)
  • Educational package to train future NMR users


  • TopSpin provides full control of your spectrometer.
  • Extensive functionality for processing, displaying and analyses in one tool – time saving and without loss of accuracy.
  • The ideal tool for NMR experts as well as for NMR novices
  • Higher sample throughput and therefore higher cost efficiency


Supported Operating Systems

  • 64-bit operating system required for TopSpin
  • Windows 10, 11 or AlmaLinux 9.2 required for spectrometer control. CentOS 7 is also supported, however it reaches its end of live at June 30 2024.
  • Processing version of TopSpin are available for Windows 10, 11, AlmaLinux 9.2, CentOS 7, and macOS
  • Detailed list of supported operating systems is available here (requires login)

Detailed information about licences and more can be found in the TopSpin FAQ

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Service & Life Cycle Support for Magnetic Resonance and Preclinical Imaging

Bruker’s commitment to provide customers with unparalleled help throughout the buying cycle, from initial inquiry to evaluation, installation, and the lifetime of the instrument is now characterized by the LabScape service concept.

LabScape Maintenance Agreements, On-Site On-Demand and Enhance Your Lab are designed to offer a new approach to maintenance and service for the modern laboratory

Connexus – Connecting Labs

Connexus® brings clients in need of advanced analytical techniques together with labs that have available capacity on their high-tech scientific NMR instruments*.

*The new Bruker BioSpin online platform Connexus is available in selected European countries