Metal Analysis in Tissues, Blood, Urine and other Body Fluids
Small biomedical research labs typically depend on external service labs with sophisticated lab infrastructure to run ICP-MS. But long waiting times and high costs are not acceptable for most researchers. TXRF is a powerful and cost-efficient alternative for any lab environment.
- TXRF spectrometer are easy to install and do not require a sophisticated lab infrastructure (exhausts, gas lines etc.)
- TXRF requires a fast and simple sample preparation only
- For the analysis of essential elements like Fe, Cu, Se, P, Ca etc. detection limits in the ppb range are achieved
Typical biomedical applications where TXRF is successfully used:
- Au, P nanoparticles in vascular science
- Se analysis in body fluids
- Elemental bio-markers for Prostate cancer detection
- Research on Alzheimer‘s disease
- Contaminant analysis of hemp
- Cancer research and chemotherapeutic agents
Related Publications
- Pattern of Altered Plasma Elemental Phosphorus, Calcium, Zinc, and Iron in Alzheimer’s Disease
- Method for measurement of serum copper, zinc and selenium using total reflection X-ray fluorescence spectroscopy on the PICOFOX analyser: Validation and comparison with atomic absorption spectroscopy and inductively coupled plasma mass spectrometry
- Severe selenium deficits in pregnant women irrespective of autoimmune thyroid disease in an area with marginal selenium intake
- The elemental changes occurring in the rat liver after exposure to PEG-coated iron oxide nanoparticles: total reflection x-ray fluorescence (TXRF) spectroscopy study