Preclinical MRI

ParaVision 360

Most advanced preclinical imaging software

Consistent Quantification

Intuitive Use


Log4j critical issue

The discovery of vulnerability of the Log4J library (CVE-2021-44228) prompted our software teams to investigate the problem and its impact on our software and also on our customers. Our investigation shows, that the ParaVision software does not use the log4j library, but Topspin 4 versions needed for ParaVision 360 operation of MR systems use the affected versions of the log4j library. However, we do not believe at this time that the Log4J gap can affect the safety of the MR spectrometer (or processing workstation) in any way. Logging is done entirely internally without involving user input, so we do not currently see any way in which the issue could be exploited.

The latest version of Bruker Log4j patch is available here. The evaluation of the Log4j issue continues. We recommend to regularly check this page for updates.

Consistent Quantification
Highest accuracy in all research stages, from set-up to quantification, from day to day, and from subject to subject leads to the most consistent, reliable data
Greatest Imaging Power
Extensive and innovative range of methods combined with sophisticated viewing, reconstruction, and analysis tools provide the most information from imaging subjects
Seamless Multimodal Imaging
Uniformity across MRI, PET, and µCT for intuitive use
ParaVision 360 Brochure

Focusing on consistent quantification, ParaVision 360 makes scanning even more intuitive, while maintaining the full flexibility that Bruker users praise. The enlarged MRI sequence portfolio, which is exclusive to Bruker, and the powerful image data evaluation functions lead to maximum proficiency in scanning and analysis, while the simplicity and uniformity across the range of instrumentation allows operators to put their focus on their research.

ParaVision 360 3.3 is now available

MRI Highlights of ParaVision 360 3.3

Acceleration Suite Extension

ParaVision 360 3.3 continues to expand the ParaVision Acceleration Suite.

  • Compressed Sensing
  • POCS reconstruction for Partial Fourier

Greater RARE Flexibility

The RARE phase encoding has been completely redefined to provide greater T2-weighted imaging flexibility allowing freely selectable TE. Additionally, the newly introduced RAREvfl method enables fast T2-weighted 3D imaging.

  • Freely selectable TE in standard RARE
  • RAREvfl
RAREvfl enables extremely fast T2-weighted isotropic images: Rat brain, resolution: 175 µm³, scan time: 2:24 min

Improved Cardiac Imaging

Acceleration techniques are extremely valuable in cardiac studies, where the length of individual measurements is often limited by the instability of these models. In ParaVision 360 3.3, new methods have been introduced to significantly facilitate these measurements.

  • SPIRiT

For more information on cardiac imaging, please read here.

Compressed Sensing image acquisition at a fraction of the original acquisition time
Acq. Time: ~ 6 min (Trig.) GRAPPA Fact: N.A
Acq. Time: ~ 3 min 10 s (Trig.) GRAPPA Fact: 2
Acq. Time: ~ 2 min 10 s (Trig.) GRAPPA Fact: 3

PEAK GRAPPA enables acquisition of high-quality CINE data in a significantly reduced measurement time. FcFLASH with (156 x 156) µm² in plane resolution



Cross-modality Highlights

  • Common terminology between instruments, common integrated multimodal workflows, and common image processing, viewing, and analysis tools and functionalities for optimal clarity
  • Animal Transport System control via touchscreen1
  • Multi-station image acquisition and imaging stitching1
  • Simple selection of prone or supine viewing
  • Automatic 3D image fusion
  • MR Method development framework
  • Drag and drop image processing
  • Advanced intensity based image registration
  • ROIs with thresholding, seeded region growing, and freehand definition
  • On-the-fly quantitative image mapping
  • Data browser with simple search functions for accessing stored protocols and recorded data
  • Database and archiving and report creation
  • An Acceleration Suite including Compressed Sensing, Simultaneous Multislice Imaging, Partial Fourier with homodyne reconstruction, and 3D GRAPPA with CAIPIRINHA
  • Wobble control on magnet front touchscreen display²
  • SLASER single voxel spectroscopy that is robust against B1 inhomogeneities and provides less chemical shift displacement
  • Magnet status display in ParaVision and remote instrument monitoring option

1Available for BioSpec 3T, Inline PET/MR, and PET/CT Si78
2For instruments with Animal Transport System

Highlights for MRI

  • Over 100 validated and ready-to-use in vivo protocols and scan programs for mice and rats with integrated examination guide for optimal scanning navigation and reproducibility
  • MRI CASL workflow package for optimal scanning and consistency
  • IntraGateUTE for virtually flow-artifact free cardiac scanning
  • Dynamic shimming capability1
  • B1 optimization and mapping
  • Fat-water separation imaging
  • Fat chemical shift corrected images
  • 3D GRAPPA and Compressed Sensing2
  • Fast online decisions and real-time calculations on all channels
  • MRI pulse program display

1 Work in progress research feature. Outcomes depend on the available shim hardware

2 Compressed Sensing is work in progress

Highlights for PET

  • MRI or CT based attenuation corrections with automatic loading of animal cradle and MRI coil and individual calculation of subject
  • Static, multi-stage, dynamic imaging
  • Wireless cardiac PET/MR imaging
  • Kinetic time course image reconstruction and segmentation
  • TAC display with Patlak fit for kinetic modeling
  • Advanced DOI
  • Scatter, randoms, isotope decay, and dead-time corrections
  • Custom isotope profiles

Highlights for µCT

  • Static, multi-stage, dynamic imaging
  • 3D/2D
  • Step & shoot or continuous
  • Ultrafast low dose protocols
  • Cardiac & respiratory gating
  • Real-time adjustments preview
  • Smoothing, beam hardening & ring corrections
  • Hounsfield scaling 





Service & Life Cycle Support for Magnetic Resonance and Preclinical Imaging

Bruker’s commitment to provide customers with unparalleled help throughout the buying cycle, from initial inquiry to evaluation, installation, and the lifetime of the instrument is now characterized by the LabScape service concept.

LabScape Maintenance Agreements, On-Site On-Demand and Enhance Your Lab are designed to offer a new approach to maintenance and service for the modern laboratory