Transforming Chemical Analysis
for the Industry
in recurring tasks such as formulation screening within the chemical manufacturing
industry. Bruker’s new NMR-based Avance Chemical Profiling Module simplifies these tasks.
It enables the identification and quantification of constituents in a mixture in raw
materials, process intermediates, and final product formulations, enhancing both
quality and efficiency across R&D, pilot, and large-scale production processes.
Highlights
Setting New Efficiency Standards by Applying High Performing Analytical Technology
Today's world’s leading chemical companies are committed to sustainability. Their goal is not just to develop chemistry, but to develop chemistry that prioritizes sustainability and environmental responsibility. They strive to drive a greener and more sustainable future.
That is why they need advanced analytical solutions to help create greener valued products while growing profitability.
Bruker BioSpin has been developing cutting-edge technologies in the field of NMR for more than 60 years. The Avance series floor-standing NMR spectrometers are widely applied in various industrial market segments at a variety of value chain positions helping industries meet their goals in product innovation.
Increasing Process Efficiency and Consistency with NMR Chemical Mixture Analysis
New NMR-based Avance Chemical Profiling Module is a comprehensive software-based automated end-to-end workflow from sample to actionable information intelligence without the need for any spectroscopic expert interaction.
The importance of automated workflows and flexibility cannot be overstated in high-throughput environments such as production-related labs, analytical testing services, R&D centers, and pilot-upscaling support functions within centers of excellence.
Avance Chemical Profiling addresses the tasks of data processing, interpretation, and report filing for NMR data of chemical mixtures allowing identification and quantification of constituents in incoming goods, process intermediates, and final product formulations to improve both, quality, and efficiency in R&D lab-scale, pilot, and volume production processes.
The database-driven solution is customizable by in-house NMR experts allowing for application on a variety of use cases.
Features
- Most-modern automation software for identification and quantification of substances in pure form or in mixtures
- Full integration into TopSpin® and IconNMRTM allows for comprehensive workflow creation from sample to actionable information intelligence
- New-standard-setting in external and internal NMR reference management
- Best-in-class ease of use and intuitive method creation
- NMR-Expert-created analytical testing methods become executable for spectroscopic non-experts by the push of a button
- Operator-independent high-throughput testing allows for optimized result comparability and lab-to-lab method harmonization
- Full on-premise installation ensures IP security and method ownership
Benefits
Automation Saves Your Time
Automated analysis software for identification and quantification of substances in pure form or mixtures
Automated Sample-to-Report methods directly available via IconNMR™ or via TopSpin® for faster identification and quantification at the push of (one) button
Different report formats: PDF, XML and interactive results directly accessible on the software interface
Highly accurate and reproducible results
Sample handling, data acquisition, and initial raw data processing is fully automated
No Expertise Needed
- Easy-to-read report by spectroscopic non-expert including consistency check
- Operator independent results
- Full customer ownership of methods and databases
- Multi-page report with results, analysis, consistency check, analysis and processing parameters used
Use Cases Expansion
- Allows your NMR instrument to do much more than structure elucidation
- Allow tailored testing services at no additional cost including re-process of existing data and improving retrospective data analysis capabilities
- User customized chemical compound database; easy database expansion possible
- Method and database can be easily deployed in other locations across same organization for a distributed lab topology deployment (DLT)
Unlocking NMR Potential: Elevating NMR beyond Structural Elucidation
Unravel NMR Efficiency in R&D lab
Your Every Day NMR Challenges:
As a chemist at the forefront of innovation, you’re no stranger to routine NMR analysis. Day in and day out, you handle critical tasks:
- Repetitve monitoring of formulations and synthesis output
- Repetitve analysis of media, intermediates, raw materials, stock solutions
- Method definition and roll-out validation for manufacturing (pilot or volume)
The Avance Chemical Profiling Solution will support you in:
- Increase throughput without limiting focus of highly trainend experts
- Improve statistical data interpretation via increased testing frequency
- Make results more comparable by operator-independent report generation
- Roll-out expert-developed testing methods in non-expert environments
- Share spectral databases and methods throughout your enire organization
Elevate NMR in Manufacturing
Your Everyday NMR Challenges:
As a manufacturing professional, you’re the guardian of quality and efficiency. These tasks are your bread and butter:
- Quality control testing of products
- Incoming goods control screening
- Process intermediates anaylsis for trouble shooting and failure analysis
The Avance Chemical Profiling Solution will support you in:
- Increase throughput with automated sample-to-report routines
- Obtain operator independent results in multi-shift environments
- Standardize and harmonize testing methods across different product lines and production sites
- Reduce time-to-result with optimized batch-release testing
- Scale to different product lines without additional costs
- Increase IP security by on-premise installation
Expand NMR reach
Your Everyday NMR Chalenges:
As an NMR-based Testing service provider, your days are filled with typical tasks:
- Analyzing samples of internal or external customers
- Apply use-case specific methods but repeat them often
- File analysis reports on foreign samples
The Avance Chemical Profiling Solution will support you in:
- Increase throughput with automated sample-to-report routines
- Create different methods for a variety of use-cases
- Standardize and harmonize testing methods for all your customers
- Reduce time-to-result for increased customer satisfaction
- Scale to different new business opportunities without additional costs
Your NMR Capacity Awaits
Your Everyday NMR Challenge:
As a laboratory chemist, you face recurrent tasks but think your NMR instrument hums with untapped potential
- Structure elucidation by NMR
- Special analytical escalation cases only
- Challenging analytical questions which cannot be solved by other technique
The Avance Chemical Profiling Solution can further support you in:
- Extend your portfolio with identification and quantification service offerings
- Offer services to neighboring departments at no additional cost
- Utilize unused measurement time during night for fully automated analysis with no manual data interpretation
- Only develop a new method but let your NMR execute it autonomously
- Justify NMR investments with multi-purpose applications
- Make NMR more relevant within your organization
Are you living in a Distributed Lab Topology Environment?
Globally organized companies might request from their labs these duties
- Method developed on R&D High-Resolution (HiRes) NMR systems
- Pilot manufacturing support by R&D department
- Volume manufacturing method development for non-expert operation (QC)
- QC method validation via R&D method
The Avance Chemical Profiling Solution will support you in:
- Direct HiRes NMR method roll-out to QC if needed
- HiRes NMR to benchtop NMR method translation if possible
- Direct (HiRes/HiRes) or In-Tech (HiRes/Benchtop) method validation decreases time-to-market
- Database-driven method scaling opportunity to other product lines (same instrument possible)
