Simultaneous PET/MR Imaging for Preclinical Research

Capture Molecular and Anatomical Insights in One Scan

Bruker's PET Inserts for BioSpec MRI systems enable simultaneous PET/MR imaging in mice and rats, allowing researchers to acquire molecular, functional, anatomical, and metabolic information during a single imaging session. By collecting PET and MRI data at the same time, scientists can achieve precise spatial and temporal correlation of biological processes, leading to deeper insights into disease mechanisms, therapeutic response, and biomarker development.

Unlike sequential imaging workflows, simultaneous PET/MR reduces variability between scans, streamlines study workflows, and improves data consistency, helping researchers generate more robust and translatable results.

Seamless Integration with ParaVision 360

Fully integrated into ParaVision 360 imaging software, Bruker's PET Insert enables researchers to perform simultaneous PET/MR imaging through familiar BioSpec MRI workflows and software tools.
Users can:

• Acquire synchronized PET and MRI datasets in a single session
  
• Leverage existing MRI workflows and expertise
  
• Simplify study setup and operation
  
• Accelerate data acquisition and analysis
  
• Maintain established imaging protocols without workflow disruption

Designed for Advanced Preclinical PET/MR Applications

Bruker's PET/MR solutions support a broad range of molecular imaging and translational research applications, including:

• Oncology and cancer biology
  
• Neuroscience and neurodegenerative disease research
  
• Cardiology and cardiovascular imaging
  
• Immunology and immune response monitoring
  
• Theranostics development
  
• Novel PET radiotracer development and validation
  
• Longitudinal disease monitoring

Why Choose Bruker PET/MR?

Bruker's integrated PET/MR solution combines high-performance molecular imaging with industry-leading preclinical MRI, enabling researchers to capture complementary biological information in real time. The result is a more complete understanding of disease processes, improved study efficiency, and greater confidence in translational research outcomes.

Powered by Bruker’s true Depth of Interaction (DOI) measurement

Accurate positioning of detected coincidence events within the detector crystals across the entire FOV ensures optimal quantification accuracy and spatial resolution, while enabling rapid reconstruction of multi-animal and whole-body scans under realistic laboratory conditions.

Key Benefits:

• High PET sensitivity for detecting subtle biological signals
• High count-rate performance for dynamic and demanding studies
  
• MRI-compatible design for interference-free simultaneous imaging
  
• Reliable and reproducible results that support translational research
• Real time reconstruction with Bruker Clarity PET reconstruction

PET Insert Si 103 Hardware Workflow

By combining highly sensitive PET with multiparametric MRI, simultaneous PET/MR provides deeper insight into tumor biology, brain function, cardiac physiology, and other complex disease processes. This multimodal approach enables comprehensive characterization of molecular, functional, and structural changes within the same imaging session, supporting more reliable quantification, improved translational relevance, and faster scientific discovery.