The presentation will give a current overview of label-free high-throughput MALDI TOF mass spectrometry and its use in drug discovery screening. It will explain the basics of MALDI TOF mass spectrometry and the benefits of label-free screening compared to current labeled approaches. Data presented will focus on enzymes in the ubiquitin system (deubiquitylases, E2/E3 ligases) and protein kinases.
Professor of Proteomics at Newcastle University
For Research Use Only. Not for use in clinical diagnostic procedures.