Banner webinar june 18 2020 new

Quantitative evaluation of pulmonary function with hyperpolarized xenon gas MR

Hyperpolarized 129Xe MR has been proven to be a powerful tool to evaluate the pulmonary function and has been widely used to study various lung diseases. Preclinical studies have advantages in exploring the feasibility of hyperpolarized 129Xe MR in diagnosing lung diseases and developing new techniques and application strategies.

Overview

In this webinar, Prof. Xin Zhou, the vice director of Innovation Academy for Precision Measurement Science and Technology, Chinese Academy of Sciences (CAS) in Wuhan, China, will give a comprehensive introduction to the application of hyperpolarized 129Xe gas MR, based on his research in this field for 2 decades. He will show the technique of chemical exchange saturation transfer (CEST), diffusion kurtosis imaging (DKI), and more, and present examples in detecting the gas-exchange function and microstructure in rodent models of lung disease. The fast acquisition and reconstruction techniques of hyperpolarized 129Xe MRI such as compressed sensing and deep learning will be also included. He will also discuss imaging and data analysis considerations for 129Xe brain imaging.

What to expect

In this webinar, Prof. Xin Zhou will show the advanced application of hyperpolarized 129Xe MR in detecting the gas-exchange function and microstructure in rodent models of lung disease and share the latest techniques of fast acquisition and reconstruction in hyperpolarized 129Xe MRI. Imaging and data analysis considerations for 129Xe brain imaging will also be discussed.

Key topics

Lung function assessment

  • Detection of morphological parameters
  • Indirect and direct detection of gas-exchange function
  • Applications in lung disease models


Fast MRI technique

  • Deep learning
  • Compressed sensing
  • Fast imaging strategies within single-breath

Brain imaging

  • Optimization of T1
  • Applications in stroke

Who should attend?

Researchers interested in pulmonary diseases and pulmonary imaging techniques and those focused on lung MR with hyperpolarized gas.

Speaker

Dr. Xin Zhou
Dr. Xin Zhou
Vice director of Innovation Academy for Precision Measurement Science and Technology, Chinese Academy of Sciences (CAS)
Prof. Xin Zhou is the vice director of Innovation Academy for Precision Measurement Science and Technology, Chinese Academy of Sciences (CAS) in Wuhan, China. Since 2017, he has also been the vice director of State Key Laboratory of Magnetic Resonance and Atomic and Molecular Physics, National Center for Magnetic Resonance in Wuhan. Professor Zhou is the pioneer of polarized 129Xe imaging in China. He is interested in ultrasensitive magnetic resonance imaging (MRI) instruments, techniques and methodology as well as biosensors for medical imaging. His group is group independently designed and developed a hyperpolarizer for gas measurements in lung with MRI, providing not only microstructural but also gas-exchange functional images of the lungs.